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Protocol for Construction of Genome-Wide Epistatic SNP Networks Using WISH-R Package.
Kadarmideen HN, Carmelo VAO. Kadarmideen HN, et al. Methods Mol Biol. 2021;2212:155-168. doi: 10.1007/978-1-0716-0947-7_10. Methods Mol Biol. 2021. PMID: 33733355
However, there is no straightforward way to compute a large number of pairwise epistasis among millions of variants along the whole genome, relate them to phenotypes or diseases, and visualize them. ...
However, there is no straightforward way to compute a large number of pairwise epistasis among millions of variants along the whole g …
A Novel Vision-Enhancing Technology for Low-Vision Impairments.
Lodato C, Ribino P. Lodato C, et al. J Med Syst. 2018 Nov 7;42(12):256. doi: 10.1007/s10916-018-1108-1. J Med Syst. 2018. PMID: 30406503
In particular, degenerative diseases of the retina such as macular senile degenerations are on the rise and affect millions of people with hundreds of thousands of new cases each year. ...
In particular, degenerative diseases of the retina such as macular senile degenerations are on the rise and affect millions of people …
Forest tree species distribution for Europe 2000-2020: mapping potential and realized distributions using spatiotemporal machine learning.
Bonannella C, Hengl T, Heisig J, Parente L, Wright MN, Herold M, de Bruin S. Bonannella C, et al. PeerJ. 2022 Jul 25;10:e13728. doi: 10.7717/peerj.13728. eCollection 2022. PeerJ. 2022. PMID: 35910765 Free PMC article.
., Quercus suber L. and Salix caprea L.) at high spatial resolution (30 m). Tree occurrence data for a total of three million of points was used to train different algorithms: random forest, gradient-boosted trees, generalized linear models, k-nearest neighbors, CART and a …
., Quercus suber L. and Salix caprea L.) at high spatial resolution (30 m). Tree occurrence data for a total of three million of poin …
Transcriptional Profiling of Immune-Related Genes in Leishmania infantum-Infected Mice: Identification of Potential Biomarkers of Infection and Progression of Disease.
Ontoria E, Hernández-Santana YE, González-García AC, López MC, Valladares B, Carmelo E. Ontoria E, et al. Front Cell Infect Microbiol. 2018 Jun 26;8:197. doi: 10.3389/fcimb.2018.00197. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 30013952 Free PMC article.
Leishmania spp. is a protozoan parasite that affects millions of people around the world. At present, there is no effective vaccine to prevent leishmaniases in humans. ...
Leishmania spp. is a protozoan parasite that affects millions of people around the world. At present, there is no effective vaccine t …
Repeated intra-articular administration of equine allogeneic peripheral blood-derived mesenchymal stem cells does not induce a cellular and humoral immune response in horses.
Van Hecke L, Magri C, Duchateau L, Beerts C, Geburek F, Suls M, Da Dalt L, Patruno M, Saunders J, Broeckx SY, Depuydt E, Spaas JH. Van Hecke L, et al. Vet Immunol Immunopathol. 2021 Sep;239:110306. doi: 10.1016/j.vetimm.2021.110306. Epub 2021 Aug 2. Vet Immunol Immunopathol. 2021. PMID: 34365135 Free article.
METHODS: Current retrospective study assessed the cellular and humoral immunogenicity of ten jumping and dressage horses with naturally occurring degenerative joint disease which were treated 3 times intra-articularly with a 1 mL stem cell suspension containing 1.4-2.5 million …
METHODS: Current retrospective study assessed the cellular and humoral immunogenicity of ten jumping and dressage horses with naturally occu …
Stirred tank bioreactor culture combined with serum-/xenogeneic-free culture medium enables an efficient expansion of umbilical cord-derived mesenchymal stem/stromal cells.
Mizukami A, Fernandes-Platzgummer A, Carmelo JG, Swiech K, Covas DT, Cabral JM, da Silva CL. Mizukami A, et al. Biotechnol J. 2016 Aug;11(8):1048-59. doi: 10.1002/biot.201500532. Epub 2016 Jun 13. Biotechnol J. 2016. PMID: 27168373
The established protocol was then implemented in a stirred-tank bioreactor (800 mL working volume) (n = 3) yielding 115 million cells after 4 days. Upon expansion under stirred conditions, cells retained their differentiation ability and immunomodulatory potential. ...
The established protocol was then implemented in a stirred-tank bioreactor (800 mL working volume) (n = 3) yielding 115 million cells …