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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1951 1
1952 2
1955 1
1957 1
1960 2
1961 2
1963 5
1964 7
1965 6
1966 3
1967 6
1968 10
1969 6
1970 9
1971 17
1972 9
1973 13
1974 12
1975 16
1976 8
1977 13
1978 13
1979 15
1980 17
1981 23
1982 41
1983 25
1984 24
1985 27
1986 31
1987 31
1988 44
1989 44
1990 41
1991 49
1992 39
1993 40
1994 34
1995 48
1996 52
1997 53
1998 60
1999 53
2000 51
2001 57
2002 47
2003 53
2004 76
2005 63
2006 61
2007 79
2008 87
2009 79
2010 116
2011 112
2012 120
2013 130
2014 149
2015 172
2016 201
2017 214
2018 230
2019 239
2020 243
2021 268
2022 255
2023 273
2024 80

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3,960 results

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43 articles found by citation matching

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Page 1
Microglia in Alzheimer's disease.
Hansen DV, Hanson JE, Sheng M. Hansen DV, et al. J Cell Biol. 2018 Feb 5;217(2):459-472. doi: 10.1083/jcb.201709069. Epub 2017 Dec 1. J Cell Biol. 2018. PMID: 29196460 Free PMC article. Review.
Proliferation and activation of microglia in the brain, concentrated around amyloid plaques, is a prominent feature of Alzheimer's disease (AD). ...The majority of risk genes for AD are highly expressed (and many are selectively expressed) by microglia in the brain. …
Proliferation and activation of microglia in the brain, concentrated around amyloid plaques, is a prominent feature of Alzheimer's di …
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.
Horsager J, Andersen KB, Knudsen K, Skjærbæk C, Fedorova TD, Okkels N, Schaeffer E, Bonkat SK, Geday J, Otto M, Sommerauer M, Danielsen EH, Bech E, Kraft J, Munk OL, Hansen SD, Pavese N, Göder R, Brooks DJ, Berg D, Borghammer P. Horsager J, et al. Brain. 2020 Oct 1;143(10):3077-3088. doi: 10.1093/brain/awaa238. Brain. 2020. PMID: 32830221
We have hypothesized that Parkinson's disease comprises two subtypes. A brain-first (top-down) type, where alpha-synuclein pathology initially arises in the brain with secondary spreading to the peripheral autonomic nervous system; and a body-first (bottom-up) type, …
We have hypothesized that Parkinson's disease comprises two subtypes. A brain-first (top-down) type, where alpha-synuclein pathology …
Whole-brain activation signatures of weight-lowering drugs.
Hansen HH, Perens J, Roostalu U, Skytte JL, Salinas CG, Barkholt P, Thorbek DD, Rigbolt KTG, Vrang N, Jelsing J, Hecksher-Sørensen J. Hansen HH, et al. Mol Metab. 2021 May;47:101171. doi: 10.1016/j.molmet.2021.101171. Epub 2021 Jan 30. Mol Metab. 2021. PMID: 33529728 Free PMC article.
RESULTS: The whole-brain analysis comprised 308 atlas-defined mouse brain areas. To enable fast and efficient data mining, a web-based 3D imaging data viewer was developed. All weight-lowering drugs demonstrated brain-wide responses with notable similarities …
RESULTS: The whole-brain analysis comprised 308 atlas-defined mouse brain areas. To enable fast and efficient data mining, a w …
Anaesthesia for the Growing Brain.
Raviraj D, Engelhardt T, Hansen TG. Raviraj D, et al. Curr Pharm Des. 2019;25(19):2165-2170. doi: 10.2174/1381612825666190702151030. Curr Pharm Des. 2019. PMID: 31267863 Review.
Despite the long history of paediatric anaesthesia, there is still much to be discovered regarding how exposure to anaesthesia affects the developing brain. Given that commonly used anaesthetic agents are thought to exert their effect via N-Methyl-D-Aspartate (NMDA) and ga …
Despite the long history of paediatric anaesthesia, there is still much to be discovered regarding how exposure to anaesthesia affects the d …
In vivo mapping of pharmacologically induced functional reorganization onto the human brain's neurotransmitter landscape.
Luppi AI, Hansen JY, Adapa R, Carhart-Harris RL, Roseman L, Timmermann C, Golkowski D, Ranft A, Ilg R, Jordan D, Bonhomme V, Vanhaudenhuyse A, Demertzi A, Jaquet O, Bahri MA, Alnagger NLN, Cardone P, Peattie ARD, Manktelow AE, de Araujo DB, Sensi SL, Owen AM, Naci L, Menon DK, Misic B, Stamatakis EA. Luppi AI, et al. Sci Adv. 2023 Jun 16;9(24):eadf8332. doi: 10.1126/sciadv.adf8332. Epub 2023 Jun 14. Sci Adv. 2023. PMID: 37315149 Free PMC article.
To understand how pharmacological interventions can exert their powerful effects on brain function, we need to understand how they engage the brain's rich neurotransmitter landscape. ...Collectively, these results highlight rich statistical patterns relating …
To understand how pharmacological interventions can exert their powerful effects on brain function, we need to understand how they en …
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex.
Hansen JY, Shafiei G, Markello RD, Smart K, Cox SML, Nørgaard M, Beliveau V, Wu Y, Gallezot JD, Aumont É, Servaes S, Scala SG, DuBois JM, Wainstein G, Bezgin G, Funck T, Schmitz TW, Spreng RN, Galovic M, Koepp MJ, Duncan JS, Coles JP, Fryer TD, Aigbirhio FI, McGinnity CJ, Hammers A, Soucy JP, Baillet S, Guimond S, Hietala J, Bedard MA, Leyton M, Kobayashi E, Rosa-Neto P, Ganz M, Knudsen GM, Palomero-Gallagher N, Shine JM, Carson RE, Tuominen L, Dagher A, Misic B. Hansen JY, et al. Nat Neurosci. 2022 Nov;25(11):1569-1581. doi: 10.1038/s41593-022-01186-3. Epub 2022 Oct 27. Nat Neurosci. 2022. PMID: 36303070 Free PMC article.
Here we collate positron emission tomography data from more than 1,200 healthy individuals to construct a whole-brain three-dimensional normative atlas of 19 receptors and transporters across nine different neurotransmitter systems. ...We replicated all findings in an inde …
Here we collate positron emission tomography data from more than 1,200 healthy individuals to construct a whole-brain three-dimension …
Endothelial cells and macrophages as allies in the healthy and diseased brain.
Denes A, Hansen CE, Oezorhan U, Figuerola S, de Vries HE, Sorokin L, Planas AM, Engelhardt B, Schwaninger M. Denes A, et al. Acta Neuropathol. 2024 Feb 12;147(1):38. doi: 10.1007/s00401-024-02695-0. Acta Neuropathol. 2024. PMID: 38347307 Free PMC article. Review.
Recent progress has revealed that different macrophage populations in the CNS and a subset of brain endothelial cells are derived from the same erythromyeloid progenitor cells. ...In adults, microglia and CAMs have been implicated in regulating the patency and diameter of …
Recent progress has revealed that different macrophage populations in the CNS and a subset of brain endothelial cells are derived fro …
Bilirubin oxidation in brain.
Hansen TW. Hansen TW. Mol Genet Metab. 2000 Sep-Oct;71(1-2):411-7. doi: 10.1006/mgme.2000.3028. Mol Genet Metab. 2000. PMID: 11001835 Review.
Bilirubin is a product of heme catabolism which by virtue of its lipid solubility can cross the blood-brain barrier and enter the brain. Neonatal jaundice is a common transitional phenomenon which is due to the combination of increased heme catabolism and rate limit …
Bilirubin is a product of heme catabolism which by virtue of its lipid solubility can cross the blood-brain barrier and enter the …
Brain barriers and their potential role in migraine pathophysiology.
Wiggers A, Ashina H, Hadjikhani N, Sagare A, Zlokovic BV, Lauritzen M, Ashina M. Wiggers A, et al. J Headache Pain. 2022 Jan 26;23(1):16. doi: 10.1186/s10194-021-01365-w. J Headache Pain. 2022. PMID: 35081902 Free PMC article. Review.
In this context, it has been hypothesized that transient dysfunction of brain barriers before or during migraine attacks might facilitate the passage of migraine-inducing peptides into the central nervous system. Here, we review evidence suggestive of brain barrier …
In this context, it has been hypothesized that transient dysfunction of brain barriers before or during migraine attacks might facili …
Bilirubin brain toxicity.
Hansen TW. Hansen TW. J Perinatol. 2001 Dec;21 Suppl 1:S48-51; discussion S59-62. doi: 10.1038/sj.jp.7210634. J Perinatol. 2001. PMID: 11803417
The rate of bilirubin entry into brain, as well as the degree of retention and rate of clearance from brain, depends on which of these circumstances are operative. ...Bilirubin appears to distribute differentially to brain subcellular compartments and is oxid …
The rate of bilirubin entry into brain, as well as the degree of retention and rate of clearance from brain, depends on which …
3,960 results