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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
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2003 1
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2011 2
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2014 5
2015 7
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Page 1
Pathophysiological Aspects of Alcohol Metabolism in the Liver.
Hyun J, Han J, Lee C, Yoon M, Jung Y. Hyun J, et al. Int J Mol Sci. 2021 May 27;22(11):5717. doi: 10.3390/ijms22115717. Int J Mol Sci. 2021. PMID: 34071962 Free PMC article. Review.
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic or binge consumption of alcohol. The liver is the major organ that metabolizes alcohol; therefore, it is particularly sensitive to alcohol intake. ...
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic or binge consumption of alcohol. The li …
The impact of the COVID-19 pandemic on eating disorders: A systematic review.
J Devoe D, Han A, Anderson A, Katzman DK, Patten SB, Soumbasis A, Flanagan J, Paslakis G, Vyver E, Marcoux G, Dimitropoulos G. J Devoe D, et al. Int J Eat Disord. 2023 Jan;56(1):5-25. doi: 10.1002/eat.23704. Epub 2022 Apr 5. Int J Eat Disord. 2023. PMID: 35384016 Free PMC article. Review.
We found increases in eating disorder symptoms during the pandemic; this increase in eating disorder symptoms was documented in patients with common eating disorders including anorexia nervosa, binge-eating disorder, bulimia nervosa, and other specified feeding and eating …
We found increases in eating disorder symptoms during the pandemic; this increase in eating disorder symptoms was documented in patients wit …
Targeting hepatic serine-arginine protein kinase 2 ameliorates alcohol-associated liver disease by alternative splicing control of lipogenesis.
Li G, Chen H, Shen F, Smithson SB, Shealy GL, Ping Q, Liang Z, Han J, Adams AC, Li Y, Feng D, Gao B, Morita M, Han X, Huang TH, Musi N, Zang M. Li G, et al. Hepatology. 2023 Nov 1;78(5):1506-1524. doi: 10.1097/HEP.0000000000000433. Epub 2023 May 3. Hepatology. 2023. PMID: 37129868
APPROACH AND RESULTS: Serine-arginine-rich protein kinase 2 (SRPK2), a key kinase controlling alternative splicing, is activated in hepatocytes in response to alcohol, in mice with chronic-plus-binge alcohol feeding, and in patients with ALD. Such induction activates stero …
APPROACH AND RESULTS: Serine-arginine-rich protein kinase 2 (SRPK2), a key kinase controlling alternative splicing, is activated in hepatocy …
Age-dependent loss of hepatic SIRT1 enhances NLRP3 inflammasome signaling and impairs capacity for liver fibrosis resolution.
Adjei-Mosi J, Sun Q, Smithson SB, Shealy GL, Amerineni KD, Liang Z, Chen H, Wang M, Ping Q, Han J, Morita M, Kamat A, Musi N, Zang M. Adjei-Mosi J, et al. Aging Cell. 2023 May;22(5):e13811. doi: 10.1111/acel.13811. Epub 2023 Mar 31. Aging Cell. 2023. PMID: 36999514 Free PMC article.
Mechanistically, deletion of SIRT1 in hepatocytes resulted in NLRP3 and IL-1beta induction, pro-inflammatory response, and severe liver fibrosis in young mice, mimicking the ability of aging to impair the resolution of established fibrosis. In an aging mouse model, chronic-plus- …
Mechanistically, deletion of SIRT1 in hepatocytes resulted in NLRP3 and IL-1beta induction, pro-inflammatory response, and severe liver fibr …
Early adversity promotes binge-like eating habits by remodeling a leptin-responsive lateral hypothalamus-brainstem pathway.
Shin S, You IJ, Jeong M, Bae Y, Wang XY, Cawley ML, Han A, Lim BK. Shin S, et al. Nat Neurosci. 2023 Jan;26(1):79-91. doi: 10.1038/s41593-022-01208-0. Epub 2022 Dec 12. Nat Neurosci. 2023. PMID: 36510113 Free PMC article.
Early-life trauma (ELT) is a risk factor for binge eating and obesity later in life, yet the neural circuits that underlie this association have not been addressed. Here, we show in mice that downregulation of the leptin receptor (Lepr) in the lateral hypothalamus (LH) and …
Early-life trauma (ELT) is a risk factor for binge eating and obesity later in life, yet the neural circuits that underlie this assoc …
Loss of ERdj5 exacerbates oxidative stress in mice with alcoholic liver disease via suppressing Nrf2.
Hong DG, Song GY, Eom CB, Ahn JH, Kim SM, Shim A, Han YH, Roh YS, Han CY, Bae EJ, Ko HJ, Yang YM. Hong DG, et al. Free Radic Biol Med. 2022 May 1;184:42-52. doi: 10.1016/j.freeradbiomed.2022.03.027. Epub 2022 Apr 4. Free Radic Biol Med. 2022. PMID: 35390453
Hepatic Dnajc10 (ERdj5) mRNA expression was elevated in both human and mouse alcoholic hepatitis. In mice subjected to chronic and binge ethanol feeding, ERdj5 levels were also markedly increased. ...
Hepatic Dnajc10 (ERdj5) mRNA expression was elevated in both human and mouse alcoholic hepatitis. In mice subjected to chronic and binge …
Current Therapeutic Options and Potential of Mesenchymal Stem Cell Therapy for Alcoholic Liver Disease.
Han J, Lee C, Hur J, Jung Y. Han J, et al. Cells. 2022 Dec 21;12(1):22. doi: 10.3390/cells12010022. Cells. 2022. PMID: 36611816 Free PMC article. Review.
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic or binge consumption of alcohol. The therapeutic efficiency of current therapies for ALD is limited, and there is no FDA-approved therapy for ALD at present. ...
Alcoholic liver disease (ALD) is a globally prevalent chronic liver disease caused by chronic or binge consumption of alcohol. The th …
Patterns of ethanol intake in male rats with partial dopamine transporter deficiency.
Kuiper LB, Roberts JB, Estave PM, Leo D, Gainetdinov RR, Jones SR. Kuiper LB, et al. Genes Brain Behav. 2023 Dec;22(6):e12847. doi: 10.1111/gbb.12847. Epub 2023 Jul 17. Genes Brain Behav. 2023. PMID: 37461188 Free PMC article.
Growing evidence suggests that alcohol drinking is modulated by the function of the dopamine transporter (DAT), which tightly regulates extracellular dopamine concentrations. Adult male rats on a Wistar Han background (DAT+/+) and rats with a partial DAT deletion (DAT+/-) …
Growing evidence suggests that alcohol drinking is modulated by the function of the dopamine transporter (DAT), which tightly regulates extr …
Trends in binge drinking prevalence among older U.S. men and women, 2015 to 2019.
Al-Rousan T, Moore AA, Han BH, Ko R, Palamar JJ. Al-Rousan T, et al. J Am Geriatr Soc. 2022 Mar;70(3):812-819. doi: 10.1111/jgs.17573. Epub 2021 Dec 8. J Am Geriatr Soc. 2022. PMID: 34877662 Free PMC article.
BACKGROUND: Recent literature suggests that the gap in prevalence of binge drinking between men and women is closing, but little is known about sex-specific differences in trends and correlates of binge drinking among older Americans. ...Both men and women reporting …
BACKGROUND: Recent literature suggests that the gap in prevalence of binge drinking between men and women is closing, but little is k …
92 results