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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1970 2
1971 2
1972 2
1973 3
1974 2
1976 1
1977 1
1978 1
1980 1
1981 1
1982 2
1983 3
1984 4
1985 4
1986 4
1987 4
1988 9
1989 8
1990 8
1991 19
1992 22
1993 32
1994 27
1995 42
1996 24
1997 44
1998 44
1999 41
2000 30
2001 43
2002 42
2003 54
2004 83
2005 74
2006 89
2007 94
2008 107
2009 129
2010 168
2011 154
2012 178
2013 213
2014 237
2015 288
2016 286
2017 314
2018 312
2019 337
2020 373
2021 407
2022 438
2023 440
2024 195

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4,878 results

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Did you mean binding to (1,783,953 results)?
A novel tRNA-derived fragment tRF-3022b modulates cell apoptosis and M2 macrophage polarization via binding to cytokines in colorectal cancer.
Lu S, Wei X, Tao L, Dong D, Hu W, Zhang Q, Tao Y, Yu C, Sun D, Cheng H. Lu S, et al. J Hematol Oncol. 2022 Dec 16;15(1):176. doi: 10.1186/s13045-022-01388-z. J Hematol Oncol. 2022. PMID: 36527118 Free PMC article.
Silencing tRF-3022b could facilitate M2 macrophage polarization. Mechanistically, we found that tRF-3022b binds to galectin 1 (LGALS1) and macrophage migration inhibitory factor (MIF) in CRC cells and reduces polarization by regulating MIF in M2 macrophages. In conclusion, …
Silencing tRF-3022b could facilitate M2 macrophage polarization. Mechanistically, we found that tRF-3022b binds to galectin 1 (LGALS1 …
RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising antagonist of the CD40-CD40L signaling for thyroid-associated ophthalmopathy (TAO) treatment in mouse.
Chen Y, Tang R, Xiong W, Zhang F, Wang N, Xie B, Cao J, Chen Z, Ma C. Chen Y, et al. J Transl Med. 2023 Jun 18;21(1):396. doi: 10.1186/s12967-023-04217-0. J Transl Med. 2023. PMID: 37331977 Free PMC article.
The CD40-CD40L pathway has been regarded as a potential molecular mechanism contributing to the development and progression of TAO, and RNA aptamers with specific binding affinity to CD40 (CD40Apt) represents a promising inhibitor of the CD40-CD40L signaling in T …
The CD40-CD40L pathway has been regarded as a potential molecular mechanism contributing to the development and progression of TAO, a …
RNA binding protein TIAR modulates HBV replication by tipping the balance of pgRNA translation.
Zhang T, Zheng H, Lu D, Guan G, Li D, Zhang J, Liu S, Zhao J, Guo JT, Lu F, Chen X. Zhang T, et al. Signal Transduct Target Ther. 2023 Sep 13;8(1):346. doi: 10.1038/s41392-023-01573-7. Signal Transduct Target Ther. 2023. PMID: 37699883 Free PMC article.
RNA immunoprecipitation (RIP) and pulldown assays further revealed that TIAR directly binds pgRNA at the 5' stem-loop (epsilon). Moreover, HBV replication or Cp expression induced the increased expression and redistribution of TIAR from the nucleus to the cytoplasm of hepa …
RNA immunoprecipitation (RIP) and pulldown assays further revealed that TIAR directly binds pgRNA at the 5' stem-loop (epsilon). More …
Plant cell-surface GIPC sphingolipids sense salt to trigger Ca2+ influx.
Jiang Z, Zhou X, Tao M, Yuan F, Liu L, Wu F, Wu X, Xiang Y, Niu Y, Liu F, Li C, Ye R, Byeon B, Xue Y, Zhao H, Wang HN, Crawford BM, Johnson DM, Hu C, Pei C, Zhou W, Swift GB, Zhang H, Vo-Dinh T, Hu Z, Siedow JN, Pei ZM. Jiang Z, et al. Nature. 2019 Aug;572(7769):341-346. doi: 10.1038/s41586-019-1449-z. Epub 2019 Jul 31. Nature. 2019. PMID: 31367039
Excess salt triggers increases in cytosolic Ca(2+) concentration, which activate Ca(2+)-binding proteins and upregulate the Na(+)/H(+) antiporter in order to remove Na(+). ...MOCA1 is required for salt-induced depolarization of the cell-surface potential, Ca(2+) spikes and …
Excess salt triggers increases in cytosolic Ca(2+) concentration, which activate Ca(2+)-binding proteins and upregulate the Na(+)/H(+ …
[Binding pancreaticogastrostomy].
Peng SY, Hong DF, Liu YB, Tan ZJ, Li JT, Tao F. Peng SY, et al. Zhonghua Wai Ke Za Zhi. 2009 Jan 15;47(2):139-42. Zhonghua Wai Ke Za Zhi. 2009. PMID: 19563012 Chinese.
OBJECTIVE: To discuss the value of a new technique of the binding pancreaticogastrostomy (BPG) in pancreaticoduodenectomy. METHODS: From May 2008 to October 2008, 15 patients were performed with BPG, included pancreatic head cancer in 7 cases, duodenal adenocarcinoma in 2 …
OBJECTIVE: To discuss the value of a new technique of the binding pancreaticogastrostomy (BPG) in pancreaticoduodenectomy. METHODS: F …
RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization.
Tao S, Xie SJ, Diao LT, Lv G, Hou YR, Hu YX, Xu WY, Du B, Xiao ZD. Tao S, et al. J Exp Clin Cancer Res. 2023 Aug 5;42(1):194. doi: 10.1186/s13046-023-02749-3. J Exp Clin Cancer Res. 2023. PMID: 37542342 Free PMC article.
BACKGROUND: RNA binding proteins (RBPs)-regulated gene expression play a vital role in various pathological processes, including the progression of cancer. ...CCDC137 markedly promoted HCC proliferation and progression in vitro and in vivo. Mechanistically, CCDC137 bind …
BACKGROUND: RNA binding proteins (RBPs)-regulated gene expression play a vital role in various pathological processes, including the …
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.
Wang Y, Guo YR, Liu K, Yin Z, Liu R, Xia Y, Tan L, Yang P, Lee JH, Li XJ, Hawke D, Zheng Y, Qian X, Lyu J, He J, Xing D, Tao YJ, Lu Z. Wang Y, et al. Nature. 2017 Dec 14;552(7684):273-277. doi: 10.1038/nature25003. Epub 2017 Dec 6. Nature. 2017. PMID: 29211711 Free PMC article.
Here we show that the alpha-ketoglutarate dehydrogenase (alpha-KGDH) complex is localized in the nucleus in human cell lines and binds to lysine acetyltransferase 2A (KAT2A, also known as GCN5) in the promoter regions of genes. We show that succinyl-coenzyme A (succinyl-Co …
Here we show that the alpha-ketoglutarate dehydrogenase (alpha-KGDH) complex is localized in the nucleus in human cell lines and binds …
Aptamer binding assays and molecular interaction studies using fluorescence anisotropy - A review.
Zhao Q, Tao J, Feng W, Uppal JS, Peng H, Le XC. Zhao Q, et al. Anal Chim Acta. 2020 Aug 15;1125:267-278. doi: 10.1016/j.aca.2020.05.061. Epub 2020 May 28. Anal Chim Acta. 2020. PMID: 32674773 Review.
We review recent advances in affinity binding assays using aptamers and FA/FP, with an emphasis on studies of molecular interactions and identification of binding sites. Aptamers provide several benefits, including the ease of labelling fluorophores on specific site …
We review recent advances in affinity binding assays using aptamers and FA/FP, with an emphasis on studies of molecular interactions …
Preface.
Tao YX. Tao YX. Prog Mol Biol Transl Sci. 2019;161:xi. doi: 10.1016/S1877-1173(19)30010-9. Prog Mol Biol Transl Sci. 2019. PMID: 30711032 No abstract available.
A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy.
Li L, Shu XS, Geng H, Ying J, Guo L, Luo J, Xiang T, Wu L, Ma BBY, Chan ATC, Zhu X, Ambinder RF, Tao Q. Li L, et al. Cell Death Differ. 2023 May;30(5):1166-1183. doi: 10.1038/s41418-023-01129-w. Epub 2023 Feb 23. Cell Death Differ. 2023. PMID: 36813924 Free PMC article.
SP0495 induces tumor cell apoptosis, cell cycle arrest, senescence and autophagy, and inhibits tumor cell growth in vitro and in vivo. Mechanistically, SP0495 binds to phosphoinositides (PtdIns(3)P, PtdIns(3,5)P2) as a lipid-binding protein, inhibits AKT phosphoryla …
SP0495 induces tumor cell apoptosis, cell cycle arrest, senescence and autophagy, and inhibits tumor cell growth in vitro and in vivo. Mecha …
4,878 results