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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1963 1
1966 1
1970 4
1971 2
1972 5
1973 2
1974 4
1975 6
1976 11
1977 6
1978 6
1979 10
1980 5
1981 10
1982 11
1983 11
1984 9
1985 10
1986 9
1987 27
1988 48
1989 48
1990 54
1991 56
1992 83
1993 95
1994 99
1995 99
1996 109
1997 94
1998 119
1999 126
2000 114
2001 134
2002 149
2003 141
2004 182
2005 181
2006 176
2007 214
2008 237
2009 215
2010 258
2011 243
2012 271
2013 339
2014 398
2015 483
2016 545
2017 539
2018 616
2019 639
2020 702
2021 719
2022 708
2023 545
2024 231

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9,111 results

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Page 1
SALL1 enforces microglia-specific DNA binding and function of SMADs to establish microglia identity.
Fixsen BR, Han CZ, Zhou Y, Spann NJ, Saisan P, Shen Z, Balak C, Sakai M, Cobo I, Holtman IR, Warden AS, Ramirez G, Collier JG, Pasillas MP, Yu M, Hu R, Li B, Belhocine S, Gosselin D, Coufal NG, Ren B, Glass CK. Fixsen BR, et al. Nat Immunol. 2023 Jul;24(7):1188-1199. doi: 10.1038/s41590-023-01528-8. Epub 2023 Jun 15. Nat Immunol. 2023. PMID: 37322178 Free PMC article.
SMAD4 binds directly to the Sall1 super-enhancer and is required for Sall1 expression, consistent with an evolutionarily conserved requirement of the TGFbeta and SMAD homologs Dpp and Mad for cell-specific expression of Spalt in the Drosophila wing. Unexpectedly, SALL1 in …
SMAD4 binds directly to the Sall1 super-enhancer and is required for Sall1 expression, consistent with an evolutionarily conserved re …
Tail engagement of arrestin at the glucagon receptor.
Chen K, Zhang C, Lin S, Yan X, Cai H, Yi C, Ma L, Chu X, Liu Y, Zhu Y, Han S, Zhao Q, Wu B. Chen K, et al. Nature. 2023 Aug;620(7975):904-910. doi: 10.1038/s41586-023-06420-x. Epub 2023 Aug 9. Nature. 2023. PMID: 37558880 Free PMC article.
Arrestins have pivotal roles in regulating G protein-coupled receptor (GPCR) signalling by desensitizing G protein activation and mediating receptor internalization(1,2). It has been proposed that the arrestin binds to the receptor in two different conformations, 'tail' an …
Arrestins have pivotal roles in regulating G protein-coupled receptor (GPCR) signalling by desensitizing G protein activation and mediating …
[Apalutamide, Erleada®].
Sautois B, Denis C. Sautois B, et al. Rev Med Liege. 2022 Oct;77(10):609-615. Rev Med Liege. 2022. PMID: 36226398 Free article. French.
10 months. Apalutamide is a nonsteroidal antiandrogen agent that binds directly to the ligand-binding domain of the androgen receptor without agonist activity. ...
10 months. Apalutamide is a nonsteroidal antiandrogen agent that binds directly to the ligand-binding domain of the androgen r …
Osteomodulin downregulation is associated with osteoarthritis development.
Zappia J, Tong Q, Van der Cruyssen R, Cornelis FMF, Lambert C, Pinto Coelho T, Grisart J, Kague E, Lories RJ, Muller M, Elewaut D, Hammond CL, Sanchez C, Henrotin Y. Zappia J, et al. Bone Res. 2023 Sep 20;11(1):49. doi: 10.1038/s41413-023-00286-5. Bone Res. 2023. PMID: 37730805 Free PMC article.
The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral bone sclerosis and spontaneous cartilage lesions. Mechanistically, OMD binds to RANKL and inhibits osteoclastogenesis, thus controll …
The expression of Omd is deeply correlated with bone and cartilage microarchitectures affecting the bone volume and the onset of subchondral …
Sex hormone-binding globulin in osteoporosis.
Hoppé E, Bouvard B, Royer M, Audran M, Legrand E. Hoppé E, et al. Joint Bone Spine. 2010 Jul;77(4):306-12. doi: 10.1016/j.jbspin.2010.03.011. Epub 2010 May 8. Joint Bone Spine. 2010. PMID: 20452803 Free article. Review.
Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds with high affinity to sex steroids, most notably 5alpha-dihydrotestosterone, testosterone, and 17beta-estradiol, thereby regulating their bioavailability and access to target cells. SHBG modulat …
Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds with high affinity to sex steroids, most notably 5alph …
Regulation of end-binding protein EB1 in the control of microtubule dynamics.
Nehlig A, Molina A, Rodrigues-Ferreira S, Honoré S, Nahmias C. Nehlig A, et al. Cell Mol Life Sci. 2017 Jul;74(13):2381-2393. doi: 10.1007/s00018-017-2476-2. Epub 2017 Feb 15. Cell Mol Life Sci. 2017. PMID: 28204846 Review.
The regulation of microtubule dynamics is critical to ensure essential cell functions, such as proper segregation of chromosomes during mitosis or cell polarity and migration. End-binding protein 1 (EB1) is a plus-end-tracking protein (+TIP) that accumulates at growing mic …
The regulation of microtubule dynamics is critical to ensure essential cell functions, such as proper segregation of chromosomes during mito …
(S)-1-(4–2-[11C]Methoxybenzyl)-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione.
Leung K. Leung K. 2009 Sep 1 [updated 2009 Sep 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2009 Sep 1 [updated 2009 Sep 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641445 Free Books & Documents. Review.
As a result, there is rapid redistribution of phosphatidylserine (PS) from the inner membrane leaflet to the outer membrane leaflet, exposing the anionic head group of PS. On the other hand, PS is also accessible for annexin V binding in necrosis because of disruption of t …
As a result, there is rapid redistribution of phosphatidylserine (PS) from the inner membrane leaflet to the outer membrane leaflet, exposin …
1-[4-(2-[18F]Fluoroethoxy)-benzyl]-5-(2-phenoxymethyl-pyrrolidine-1-sulfonyl)-1H-indole-2,3-dione.
Leung K. Leung K. 2007 Jun 28 [updated 2008 Feb 16]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2007 Jun 28 [updated 2008 Feb 16]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641249 Free Books & Documents. Review.
As a result, there is rapid redistribution of phosphatidylserine (PS) from the inner membrane leaflet to the outer membrane leaflet, exposing the anionic head group of PS. On the other hand, PS is also accessible for annexin V binding in necrosis because of disruption of t …
As a result, there is rapid redistribution of phosphatidylserine (PS) from the inner membrane leaflet to the outer membrane leaflet, exposin …
Hemagglutination assay for the estimation of a carbohydrate-binding activity and determination of its carbohydrate-binding specificity.
St-Pierre G, Sato S. St-Pierre G, et al. 2021 Oct 17 [updated 2022 Mar 30]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. 2021 Oct 17 [updated 2022 Mar 30]. In: Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, editors. Glycoscience Protocols (GlycoPODv2) [Internet]. Saitama (JP): Japan Consortium for Glycobiology and Glycotechnology; 2021–. PMID: 37590589 Free Books & Documents. Review. No abstract available.
9,111 results