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Page 1
Showing results for binding, yu
Search for binbin, yu instead (1 results)
Beyond Antibodies as Binding Partners: The Role of Antibody Mimetics in Bioanalysis.
Yu X, Yang YP, Dikici E, Deo SK, Daunert S. Yu X, et al. Annu Rev Anal Chem (Palo Alto Calif). 2017 Jun 12;10(1):293-320. doi: 10.1146/annurev-anchem-061516-045205. Epub 2017 Mar 24. Annu Rev Anal Chem (Palo Alto Calif). 2017. PMID: 28375702 Free PMC article. Review.
The emergence of novel binding proteins or antibody mimetics capable of binding to ligand analytes in a manner analogous to that of the antigen-antibody interaction has spurred increased interest in the biotechnology and bioanalytical communities. The goal is to pro …
The emergence of novel binding proteins or antibody mimetics capable of binding to ligand analytes in a manner analogous to th …
Reversible domain closure modulates GlnBP ligand binding affinity.
Chen Q, Li F, Zuo X, Chen J, Qin P, Wang C, Xu J, Yang D, Xing B, Liu Y, Jia P, Li L, Yang C, Yu D. Chen Q, et al. PLoS One. 2022 Apr 21;17(4):e0263102. doi: 10.1371/journal.pone.0263102. eCollection 2022. PLoS One. 2022. PMID: 35446849 Free PMC article.
Glutamine binding protein (GlnBP) is an Escherichia Coli periplasmic binding protein, which binds and carries glutamine to the inner membrane ATP-binding cassette (ABC) transporter. GlnBP binds the ligand with affinity around 0.1muM measured by …
Glutamine binding protein (GlnBP) is an Escherichia Coli periplasmic binding protein, which binds and carries glutamine …
PTBP1 as a potential regulator of disease.
Yu Q, Wu T, Xu W, Wei J, Zhao A, Wang M, Li M, Chi G. Yu Q, et al. Mol Cell Biochem. 2023 Dec 22. doi: 10.1007/s11010-023-04905-x. Online ahead of print. Mol Cell Biochem. 2023. PMID: 38129625 Review.
Polypyrimidine tract-binding protein 1 (PTBP1) is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, which plays a key role in alternative splicing of precursor mRNA and RNA metabolism. PTBP1 is universally expressed in various tissues and binds …
Polypyrimidine tract-binding protein 1 (PTBP1) is a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family, which plays …
Binding and cross-linking properties of galectins.
Fred Brewer C. Fred Brewer C. Biochim Biophys Acta. 2002 Sep 19;1572(2-3):255-62. doi: 10.1016/s0304-4165(02)00312-4. Biochim Biophys Acta. 2002. PMID: 12223273 Review.
For example, galectin-1, which is dimeric, binds and cross-links specific glycoprotein counter-receptors on the surface of human T-cells leading to apoptosis [J. ...This indicates that the separation and organization of signaling molecules that result from galectin-1 bi …
For example, galectin-1, which is dimeric, binds and cross-links specific glycoprotein counter-receptors on the surface of human T-ce …
Glutamate and Glycine Binding to the NMDA Receptor.
Yu A, Lau AY. Yu A, et al. Structure. 2018 Jul 3;26(7):1035-1043.e2. doi: 10.1016/j.str.2018.05.004. Epub 2018 Jun 7. Structure. 2018. PMID: 29887499 Free PMC article.
We find that positively charged residues on the surface of the GluN2A ligand-binding domain (LBD) assist glutamate binding via a "guided-diffusion" mechanism, similar in fashion to glutamate binding to the GluA2 LBD of AMPA receptors. Glutamate can also bind …
We find that positively charged residues on the surface of the GluN2A ligand-binding domain (LBD) assist glutamate binding via …
Crystal structures clarify cofactor binding of plant tyrosine decarboxylase.
Wang H, Yu J, Satoh Y, Nakagawa Y, Tanaka R, Kato K, Yao M. Wang H, et al. Biochem Biophys Res Commun. 2020 Mar 5;523(2):500-505. doi: 10.1016/j.bbrc.2019.12.077. Epub 2019 Dec 30. Biochem Biophys Res Commun. 2020. PMID: 31898973 Free article.
In this study, we focus on the PLP binding manner, and determined the crystal structures of the apo and PLP binding form of type II TyrDC from Papaver somniferum (PsTyrDCII and PsTyrDCII-PLP). ...Combining structural comparation and the obtained biochemical findings …
In this study, we focus on the PLP binding manner, and determined the crystal structures of the apo and PLP binding form of ty …
Pediatric usage of Omalizumab: A promising one.
Yu L, Zhang H, Pan J, Ye L. Yu L, et al. World Allergy Organ J. 2021 Dec 11;14(12):100614. doi: 10.1016/j.waojou.2021.100614. eCollection 2021 Dec. World Allergy Organ J. 2021. PMID: 34963793 Free PMC article. Review.
Omalizumab is the first monoclonal antibody-based medicine used in children's allergy and shows great promises. It binds to free IgE and prevents it from binding to IgE receptors, thus interrupting the IgE-dependent allergic inflammatory cascade. ...
Omalizumab is the first monoclonal antibody-based medicine used in children's allergy and shows great promises. It binds to free IgE …
The secreted micropeptide C4orf48 enhances renal fibrosis via an RNA-binding mechanism.
Yang J, Zhuang H, Li J, Nunez-Nescolarde AB, Luo N, Chen H, Li A, Qu X, Wang Q, Fan J, Bai X, Ye Z, Gu B, Meng Y, Zhang X, Wu D, Sia Y, Jiang X, Chen W, Combes AN, Nikolic-Paterson DJ, Yu X. Yang J, et al. J Clin Invest. 2024 Apr 16:e178392. doi: 10.1172/JCI178392. Online ahead of print. J Clin Invest. 2024. PMID: 38625739 Free article.
Cellular uptake of Cf48 and its pro-fibrotic response in fibroblasts operated via the transferrin receptor. RNA immunoprecipitation-sequencing identified Cf48 binding to mRNA of genes involved in the fibrotic response, including Serpine1, Acta2, Ccn2, and Col4a1. rCf48 …
Cellular uptake of Cf48 and its pro-fibrotic response in fibroblasts operated via the transferrin receptor. RNA immunoprecipitation-sequenci …
MIBPred: Ensemble Learning-Based Metal Ion-Binding Protein Classifier.
Zhang HQ, Liu SH, Li R, Yu JW, Ye DX, Yuan SS, Lin H, Huang CB, Tang H. Zhang HQ, et al. ACS Omega. 2024 Feb 8;9(7):8439-8447. doi: 10.1021/acsomega.3c09587. eCollection 2024 Feb 20. ACS Omega. 2024. PMID: 38405489 Free PMC article.
In biological organisms, metal ion-binding proteins participate in numerous metabolic activities and are closely associated with various diseases. To accurately predict whether a protein binds to metal ions and the type of metal ion-binding protein, this stud …
In biological organisms, metal ion-binding proteins participate in numerous metabolic activities and are closely associated with vari …
Role of actin filaments and cis binding in cadherin clustering and patterning.
Yu Q, Kim T, Rajagopal V. Yu Q, et al. PLoS Comput Biol. 2022 Jul 8;18(7):e1010257. doi: 10.1371/journal.pcbi.1010257. eCollection 2022 Jul. PLoS Comput Biol. 2022. PMID: 35802763 Free PMC article.
This results in changes in cadherin clustering behaviors, as reflected by differences in cluster size and distribution as well as cadherin monomer trajectory. Strong cadherin/actin binding can enhance trans and cis interactions as well as cadherin clustering. By contrast, …
This results in changes in cadherin clustering behaviors, as reflected by differences in cluster size and distribution as well as cadherin m …
32,222 results
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