To fully understand MT and its role with lead metabolism, we will describe how MT interacts with a wide variety of metals that bind in vitro. In general, affinity to the metal-binding cysteine residues of MT follows that of metal binding to thiols: Zn(II) < Pb(II
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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
1975 | 4 |
1976 | 2 |
1977 | 3 |
1978 | 1 |
1979 | 4 |
1980 | 1 |
1981 | 1 |
1982 | 3 |
1983 | 9 |
1984 | 6 |
1985 | 7 |
1986 | 5 |
1987 | 2 |
1988 | 13 |
1989 | 8 |
1990 | 8 |
1991 | 15 |
1992 | 10 |
1993 | 22 |
1994 | 19 |
1995 | 28 |
1996 | 40 |
1997 | 33 |
1998 | 51 |
1999 | 61 |
2000 | 60 |
2001 | 86 |
2002 | 104 |
2003 | 136 |
2004 | 144 |
2005 | 154 |
2006 | 163 |
2007 | 197 |
2008 | 221 |
2009 | 232 |
2010 | 259 |
2011 | 322 |
2012 | 372 |
2013 | 455 |
2014 | 497 |
2015 | 551 |
2016 | 566 |
2017 | 579 |
2018 | 665 |
2019 | 662 |
2020 | 770 |
2021 | 823 |
2022 | 875 |
2023 | 876 |
2024 | 361 |