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Year Number of Results
2004 1
2010 2
2011 1
2014 3
2015 2
2016 1
2017 1
2018 1
2019 1
2020 1
2021 4
2022 2
2023 3
2024 0

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18 results

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Page 1
Effects of Anti-Diabetic Drugs on Fracture Risk: A Systematic Review and Network Meta-Analysis.
Zhang YS, Zheng YD, Yuan Y, Chen SC, Xie BC. Zhang YS, et al. Front Endocrinol (Lausanne). 2021 Oct 14;12:735824. doi: 10.3389/fendo.2021.735824. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34721294 Free PMC article.
In terms of fractures, voglibose (0.01%) may be the safest option, and trelagliptin (13.64%) may be the worst. ...Specifically, trelagliptin raised the risk of fracture, whereas voglibose and albiglutide showed benefit with statistical difference. ...
In terms of fractures, voglibose (0.01%) may be the safest option, and trelagliptin (13.64%) may be the worst. ...Specifically, trela …
An Updated Overview of Synthetic α-glucosidase Inhibitors: Chemistry and Bioactivities.
Cai YS, Xie HX, Zhang JH, Li Y, Zhang J, Wang KM, Jiang CS. Cai YS, et al. Curr Top Med Chem. 2023;23(26):2488-2526. doi: 10.2174/0115680266260682230921054652. Curr Top Med Chem. 2023. PMID: 37818579 Review.
In the past years, three alpha-glucosidase inhibitors have been approved for clinical use, namely acarbose, voglibose, and miglitol. However, the undesirable effects associated with these carbohydrate mimic-based alpha-glucosidase inhibitors have limited their clinical app …
In the past years, three alpha-glucosidase inhibitors have been approved for clinical use, namely acarbose, voglibose, and miglitol. …
Modulating the glycemic response of starch-based foods using organic nanomaterials: strategies and opportunities.
Hassane Hamadou A, Zhang J, Li H, Chen C, Xu B. Hassane Hamadou A, et al. Crit Rev Food Sci Nutr. 2023 Nov;63(33):11942-11966. doi: 10.1080/10408398.2022.2097638. Epub 2022 Jul 28. Crit Rev Food Sci Nutr. 2023. PMID: 35900010 Review.
Overall, regulating the GI using ONMs could be a safe, robust and viable alternative compared to synthetic drugs (acarbose and voglibose) and un-encapsulated bioactive. Future researches should prioritize ONMs in real food products and evaluate their safety on a case-by-ca …
Overall, regulating the GI using ONMs could be a safe, robust and viable alternative compared to synthetic drugs (acarbose and voglibose …
Fruit, vegetables, and mushrooms for the preparation of extracts with α-amylase and α-glucosidase inhibition properties: A review.
Papoutsis K, Zhang J, Bowyer MC, Brunton N, Gibney ER, Lyng J. Papoutsis K, et al. Food Chem. 2021 Feb 15;338:128119. doi: 10.1016/j.foodchem.2020.128119. Epub 2020 Sep 17. Food Chem. 2021. PMID: 33091976 Review.
Existing enzyme inhibitors such as acarbose, miglitol, and voglibose are used for inhibiting the activity of these enzymes, however, alternative solutions are required to avoid the side-effects of using these drugs. ...
Existing enzyme inhibitors such as acarbose, miglitol, and voglibose are used for inhibiting the activity of these enzymes, however, …
Two-dimensional metal-organic framework catalyzed chemiluminescent reaction for alpha-glucosidase inhibitor screening.
Zhang Y, Li M, Li S, Fan A. Zhang Y, et al. Talanta. 2023 Nov 1;264:124748. doi: 10.1016/j.talanta.2023.124748. Epub 2023 May 30. Talanta. 2023. PMID: 37271006
Then, the luminol-H(2)O(2)-Fe-BTC CL system was applied to the detection of alpha-glucosidase (alpha-Glu) activity and screening of AGIs based on cascade enzymatic reactions using acarbose and voglibose as model drugs. The IC(50) of acarbose and voglibose was 7.39 m …
Then, the luminol-H(2)O(2)-Fe-BTC CL system was applied to the detection of alpha-glucosidase (alpha-Glu) activity and screening of AGIs bas …
Nucleotidylation of unsaturated carbasugar in validamycin biosynthesis.
Yang J, Xu H, Zhang Y, Bai L, Deng Z, Mahmud T. Yang J, et al. Org Biomol Chem. 2011 Jan 21;9(2):438-49. doi: 10.1039/c0ob00475h. Epub 2010 Oct 27. Org Biomol Chem. 2011. PMID: 20981366 Free PMC article.
Validamycin A is a member of microbial-derived C(7)N-aminocyclitol family of natural products that is widely used as crop protectant and the precursor of the antidiabetic drug voglibose. Its biosynthetic gene clusters have been identified in several Streptomyces hygroscopi …
Validamycin A is a member of microbial-derived C(7)N-aminocyclitol family of natural products that is widely used as crop protectant and the …
Voglibose Regulates the Secretion of GLP-1 Accompanied by Amelioration of Ileal Inflammatory Damage and Endoplasmic Reticulum Stress in Diabetic KKAy Mice.
Fu Y, Ji W, Liu Q, Zhang L, Li C, Huan Y, Lei L, Gao X, Chen L, Feng C, Lei L, Zhai J, Li P, Cao H, Liu S, Shen Z. Fu Y, et al. Int J Mol Sci. 2022 Dec 14;23(24):15938. doi: 10.3390/ijms232415938. Int J Mol Sci. 2022. PMID: 36555580 Free PMC article.
Recently, there has been increasing interest in the anti-inflammatory effects of voglibose on the intestine, but the underlying mechanism is not clear. This study evaluated the effects and mechanisms of voglibose on glycemic control and intestinal inflammation. Type …
Recently, there has been increasing interest in the anti-inflammatory effects of voglibose on the intestine, but the underlying mecha …
Dapagliflozin reverses the imbalance of T helper 17 and T regulatory cells by inhibiting SGK1 in a mouse model of diabetic kidney disease.
Wang D, Zhang Z, Si Z, Yang Y, Li S, Xue Y. Wang D, et al. FEBS Open Bio. 2021 May;11(5):1395-1405. doi: 10.1002/2211-5463.13147. Epub 2021 May 1. FEBS Open Bio. 2021. PMID: 33728820 Free PMC article.
This study aimed to evaluate the potential benefits of dapagliflozin (Dap) on DKD, as well as its influence on shifting renal T-cell polarization and related cytokine secretion. We treated male db/db mice with Dap or voglibose (Vog) and measured blood and kidney levels of …
This study aimed to evaluate the potential benefits of dapagliflozin (Dap) on DKD, as well as its influence on shifting renal T-cell polariz …
Transcriptional Regulation of Plant Biomass Degradation and Carbohydrate Utilization Genes in the Extreme Thermophile Caldicellulosiruptor bescii.
Rodionov DA, Rodionova IA, Rodionov VA, Arzamasov AA, Zhang K, Rubinstein GM, Tanwee TNN, Bing RG, Crosby JR, Nookaew I, Basen M, Brown SD, Wilson CM, Klingeman DM, Poole FL 2nd, Zhang Y, Kelly RM, Adams MWW. Rodionov DA, et al. mSystems. 2021 Jun 29;6(3):e0134520. doi: 10.1128/mSystems.01345-20. Epub 2021 Jun 1. mSystems. 2021. PMID: 34060910 Free PMC article.
18 results