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1966 6
1967 15
1968 7
1969 18
1970 17
1971 18
1972 23
1973 35
1974 49
1975 135
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1977 162
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1979 272
1980 315
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2001 1187
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2004 1303
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49,250 results

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Page 1
Unnatural Base Pairs for Synthetic Biology.
Saito-Tarashima N, Minakawa N. Saito-Tarashima N, et al. Chem Pharm Bull (Tokyo). 2018;66(2):132-138. doi: 10.1248/cpb.c17-00685. Chem Pharm Bull (Tokyo). 2018. PMID: 29386463 Free article. Review.
In this review, we have summarized the research effort into the development of unnatural base pairs beyond standard Watson-Crick (WC) base pairs for synthetic biology. ...Their research results demonstrate the importance of shape complementarity and st …
In this review, we have summarized the research effort into the development of unnatural base pairs beyond standard Watson-Cri …
Enzymatic construction of metal-mediated nucleic acid base pairs.
Flamme M, Figazzolo C, Gasser G, Hollenstein M. Flamme M, et al. Metallomics. 2021 Apr 21;13(4):mfab016. doi: 10.1093/mtomcs/mfab016. Metallomics. 2021. PMID: 33791776 Free article. Review.
Artificial metal base pairs have become increasingly important in nucleic acids chemistry due to their high thermal stability, water solubility, orthogonality to natural base pairs, and low cost of production. ...Herein, we discuss recent progress made …
Artificial metal base pairs have become increasingly important in nucleic acids chemistry due to their high thermal stability, …
Metal-Modified Nucleic Acids: Metal-Mediated Base Pairs, Triples, and Tetrads.
Naskar S, Guha R, Müller J. Naskar S, et al. Angew Chem Int Ed Engl. 2020 Jan 20;59(4):1397-1406. doi: 10.1002/anie.201905913. Epub 2019 Aug 21. Angew Chem Int Ed Engl. 2020. PMID: 31259475 Review.
More recently, artificial nucleosides derived from natural purine or pyrimidine bases have moved into the focus of Ag(I) -mediated base pairing, due to their expected compatibility with regular Watson-Crick base pairs. This minireview summarizes these …
More recently, artificial nucleosides derived from natural purine or pyrimidine bases have moved into the focus of Ag(I) -mediated base …
Watson-Crick versus Hoogsteen Base Pairs: Chemical Strategy to Encode and Express Genetic Information in Life.
Takahashi S, Sugimoto N. Takahashi S, et al. Acc Chem Res. 2021 May 4;54(9):2110-2120. doi: 10.1021/acs.accounts.0c00734. Epub 2021 Feb 16. Acc Chem Res. 2021. PMID: 33591181 Review.
Nucleic acids typically form a double helix structure through Watson-Crick base-pairing. In contrast, non-Watson-Crick base pairs can form other three-dimensional structures. Although it is well-known that Watson-Crick base pairs may be m …
Nucleic acids typically form a double helix structure through Watson-Crick base-pairing. In contrast, non-Watson-Crick base …
Genetic alphabet expansion technology by creating unnatural base pairs.
Kimoto M , Hirao I . Kimoto M , et al. Chem Soc Rev. 2020 Nov 7;49(21):7602-7626. doi: 10.1039/d0cs00457j. Epub 2020 Oct 5. Chem Soc Rev. 2020. PMID: 33015699 Review.
Recent advancements in the creation of artificial extra base pairs (unnatural base pairs, UBPs) are opening the door to a new research area, xenobiology, and genetic alphabet expansion technologies. UBPs that function as third base pairs …
Recent advancements in the creation of artificial extra base pairs (unnatural base pairs, UBPs) are opening the …
Electron Attachment to Wobble Base Pairs.
Narayanan S J J, Bachhar A, Tripathi D, Dutta AK. Narayanan S J J, et al. J Phys Chem A. 2023 Jan 19;127(2):457-467. doi: 10.1021/acs.jpca.2c07469. J Phys Chem A. 2023. PMID: 36622294
We have analyzed the low-energy electron attachment to wobble base pairs using the equation of motion coupled cluster method and extended basis sets. ...The calculated rate constant for the dipole-bound to valence-bound transition in wobble base pairs …
We have analyzed the low-energy electron attachment to wobble base pairs using the equation of motion coupled cluster method a …
Two are not enough: synthetic strategies and applications of unnatural base pairs.
Dörrenhaus R, Wagner PK, Kath-Schorr S. Dörrenhaus R, et al. Biol Chem. 2023 Jun 26;404(10):883-896. doi: 10.1515/hsz-2023-0169. Print 2023 Sep 26. Biol Chem. 2023. PMID: 37354104 Review.
This review focusses on the development and application of unnatural base pairs as part of an expanded genetic alphabet. Not only recent developments in "nature-like" artificial base pairs are presented, but also current synthetic methods to get access …
This review focusses on the development and application of unnatural base pairs as part of an expanded genetic alphabet. Not o …
Isostericity and tautomerism of base pairs in nucleic acids.
Westhof E. Westhof E. FEBS Lett. 2014 Aug 1;588(15):2464-9. doi: 10.1016/j.febslet.2014.06.031. Epub 2014 Jun 17. FEBS Lett. 2014. PMID: 24950426 Free article. Review.
In a given family, some of the base pairs are isosteric between them, meaning that the positions and the distances between the C1' carbon atoms are very similar. ...With the use of alternative conformations, protonated or tautomeric forms of the bases, some base …
In a given family, some of the base pairs are isosteric between them, meaning that the positions and the distances between the …
The Structural Basis for Processing of Unnatural Base Pairs by DNA Polymerases.
Marx A, Betz K. Marx A, et al. Chemistry. 2020 Mar 18;26(16):3446-3463. doi: 10.1002/chem.201903525. Epub 2020 Jan 21. Chemistry. 2020. PMID: 31544987 Free PMC article. Review.
Unnatural base pairs (UBPs) greatly increase the diversity of DNA and RNA, furthering their broad range of molecular biological and biotechnological approaches. Different candidates have been developed whereby alternative hydrogen-bonding patterns and hydrophobic an …
Unnatural base pairs (UBPs) greatly increase the diversity of DNA and RNA, furthering their broad range of molecular biologica …
49,250 results
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