Abstract
The genetic relatedness of clinical and environmental Cryptococcus neoformans strains in the Maltese Islands was investigated by randomly amplified polymorphic DNA fingerprinting with four primers. The clinical strains isolate over the course of 1 year from AIDS patients showed identical fingerprints. The electrophoretic patterns of the two clinical strains were also the most common patterns among the environmental strains, but the patterns among the environmental strains showed a wide variability and no correlation with the site of isolation.
MeSH terms
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AIDS-Related Opportunistic Infections / epidemiology
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AIDS-Related Opportunistic Infections / microbiology
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Animals
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Base Sequence
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Birds / microbiology
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Cryptococcus neoformans / classification
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Cryptococcus neoformans / genetics*
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Cryptococcus neoformans / isolation & purification
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DNA Fingerprinting
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DNA Primers / genetics
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DNA, Fungal / genetics
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DNA, Fungal / isolation & purification
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Environmental Microbiology
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Genetic Variation*
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Humans
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Malta / epidemiology
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Meningitis, Cryptococcal / complications
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Meningitis, Cryptococcal / epidemiology
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Meningitis, Cryptococcal / microbiology
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Molecular Epidemiology
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Random Amplified Polymorphic DNA Technique
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Serotyping