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Bile Acids, Gut Microbes, and the Neighborhood Food Environment-a Potential Driver of Colorectal Cancer Health Disparities.
Wolf PG, Byrd DA, Cares K, Dai H, Odoms-Young A, Gaskins HR, Ridlon JM, Tussing-Humphreys L. Wolf PG, et al. mSystems. 2022 Feb 22;7(1):e0117421. doi: 10.1128/msystems.01174-21. Epub 2022 Feb 1. mSystems. 2022. PMID: 35103491 Free PMC article. Review.
Bile acids (BAs) facilitate nutrient digestion and absorption and act as signaling molecules in a number of metabolic and inflammatory pathways. Expansion of the BA pool and increased exposure to microbial BA metabolites has been associated with increased col …
Bile acids (BAs) facilitate nutrient digestion and absorption and act as signaling molecules in a number of metabolic and inflammatory pathw …
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Williams WB, Meyerhoff RR, Edwards RJ, Li H, Manne K, Nicely NI, Henderson R, Zhou Y, Janowska K, Mansouri K, Gobeil S, Evangelous T, Hora B, Berry M, Abuahmad AY, Sprenz J, Deyton M, Stalls V, Kopp M, Hsu AL, Borgnia MJ, Stewart-Jones GBE, Lee MS, Bronkema N, Moody MA, Wiehe K, Bradley T, Alam SM, Parks RJ, Foulger A, Oguin T, Sempowski GD, Bonsignori M, LaBranche CC, Montefiori DC, Seaman M, Santra S, Perfect J, Francica JR, Lynn GM, Aussedat B, Walkowicz WE, Laga R, Kelsoe G, Saunders KO, Fera D, Kwong PD, Seder RA, Bartesaghi A, Shaw GM, Acharya P, Haynes BF. Williams WB, et al. Cell. 2021 May 27;184(11):2955-2972.e25. doi: 10.1016/j.cell.2021.04.042. Epub 2021 May 20. Cell. 2021. PMID: 34019795 Free PMC article.
Moreover, FDG precursors were predominately mutated IgM(+)IgD(+)CD27(+), thus suggesting that they originated from a pool of antigen-experienced IgM(+) or marginal zone B cells....
Moreover, FDG precursors were predominately mutated IgM(+)IgD(+)CD27(+), thus suggesting that they originated from a pool of antigen- …
LKB1 in Intestinal Epithelial Cells Regulates Bile Acid Metabolism by Modulating FGF15/19 Production.
Kim Y, Lee S, Kim S, Kim TY, Lee SH, Chang JH, Kweon MN. Kim Y, et al. Cell Mol Gastroenterol Hepatol. 2022;13(4):1121-1139. doi: 10.1016/j.jcmgh.2021.12.017. Epub 2021 Dec 29. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34973477 Free PMC article.
In this study, we investigated the regulatory role of LKB1 on bile acid (BA) homeostasis. METHODS: We generated mice with IEC-specific deletion of LKB1 (LKB1(deltaIEC)) and analyzed the characteristics of IEC development and BA level. ...Unexpectedly, BA p
In this study, we investigated the regulatory role of LKB1 on bile acid (BA) homeostasis. METHODS: We generated mice with IEC-specifi …
FXR deficiency alters bile acid pool composition and exacerbates chronic alcohol induced liver injury.
Kong B, Zhang M, Huang M, Rizzolo D, Armstrong LE, Schumacher JD, Chow MD, Lee YH, Guo GL. Kong B, et al. Dig Liver Dis. 2019 Apr;51(4):570-576. doi: 10.1016/j.dld.2018.12.026. Epub 2019 Jan 29. Dig Liver Dis. 2019. PMID: 30803859 Free PMC article.
The expression of Lcn2 was increased by ethanol treatment, despite unchanged expression of pro-inflammatory cytokines Tnfalpha, Il6 and Il-1beta. Furthermore, ethanol treatment altered bile acid (BA) homeostasis to a greater extent in FXR(-/-) mice, as well as serum and he …
The expression of Lcn2 was increased by ethanol treatment, despite unchanged expression of pro-inflammatory cytokines Tnfalpha, Il6 and Il-1 …
Effects of dietary pectin on the profile and transport of intestinal bile acids in young pigs.
Fang W, Zhang L, Meng Q, Wu W, Lee YK, Xie J, Zhang H. Fang W, et al. J Anim Sci. 2018 Nov 21;96(11):4743-4754. doi: 10.1093/jas/sky327. J Anim Sci. 2018. PMID: 30102377 Free PMC article.
Along the length of the intestine, the size and composition of BA pools vary. The ratio of primary, secondary, taurine-conjugated, and glycine-conjugated BAs in the ileal pool was about 46:15:9:30, whereas it was 28:61:1:11 in the cecum and 22:65:3:9 in the colon (P …
Along the length of the intestine, the size and composition of BA pools vary. The ratio of primary, secondary, taurine-conjugated, an …
Lessons learned from the INHANCE consortium: An overview of recent results on head and neck cancer.
Bravi F, Lee YA, Hashibe M, Boffetta P, Conway DI, Ferraroni M, La Vecchia C, Edefonti V; INHANCE Consortium investigators. Bravi F, et al. Oral Dis. 2021 Jan;27(1):73-93. doi: 10.1111/odi.13502. Epub 2020 Jul 16. Oral Dis. 2021. PMID: 32569410 Free PMC article. Review.
The beneficial effects on incidence of head and neck cancer were identified for good oral health, endogenous and exogenous hormonal factors, and selected aspects of diet related to fruit and vegetables. INHANCE has begun to develop risk prediction models and to pool follow …
The beneficial effects on incidence of head and neck cancer were identified for good oral health, endogenous and exogenous hormonal factors, …
Unraveling the Genetic Diversity and Population Structure of Bangladeshi Indigenous Cattle Populations Using 50K SNP Markers.
Bhuiyan MSA, Lee SH, Hossain SMJ, Deb GK, Afroz MF, Lee SH, Bhuiyan AKFH. Bhuiyan MSA, et al. Animals (Basel). 2021 Aug 12;11(8):2381. doi: 10.3390/ani11082381. Animals (Basel). 2021. PMID: 34438837 Free PMC article.
The admixture analysis at K = 5 and 9 suggests distinct genetic structure of the studied populations along with 1 to 4% of taurine ancestry. The effective population size suggested a limited pool of ancestors particularly for Sahiwal and North Bengal Grey cattle. ...
The admixture analysis at K = 5 and 9 suggests distinct genetic structure of the studied populations along with 1 to 4% of taurine ancestry. …
Seroprevalences of multi-pathogen and description of farm movement in pigs in two provinces in Vietnam.
Lee HS, Bui VN, Nguyen HX, Bui AN, Hoang TD, Nguyen-Viet H, Grace Randolph D, Wieland B. Lee HS, et al. BMC Vet Res. 2020 Jan 14;16(1):15. doi: 10.1186/s12917-020-2236-7. BMC Vet Res. 2020. PMID: 31937298 Free PMC article.
Some respondents (5% for exportation and 20% for importation) had moved pigs more than 6 times over the last 6 months. CONCLUSIONS: Our study provided another pool of evidence that showed that PCV2, PRRS and H. hyo are endemic in pigs in Vietnam. ...
Some respondents (5% for exportation and 20% for importation) had moved pigs more than 6 times over the last 6 months. CONCLUSIONS: Our stud …
Traceless labeling of glycoproteins and its application to the study of glycoprotein-protein interactions.
Yang YL, Lee YP, Yang YL, Lin PC. Yang YL, et al. ACS Chem Biol. 2014 Feb 21;9(2):390-7. doi: 10.1021/cb400631w. Epub 2013 Nov 8. ACS Chem Biol. 2014. PMID: 24180370
A new chemical method for the traceless labeling of glycoproteins with synthetic boronic acid (BA)-tosyl probes was successfully developed. The BA moiety acts as an affinity head to direct the formation of a cyclic boronate diester with the diol groups of glycans. . …
A new chemical method for the traceless labeling of glycoproteins with synthetic boronic acid (BA)-tosyl probes was successfully deve …
Overexpression of salicylic acid carboxyl methyltransferase reduces salicylic acid-mediated pathogen resistance in Arabidopsis thaliana.
Koo YJ, Kim MA, Kim EH, Song JT, Jung C, Moon JK, Kim JH, Seo HS, Song SI, Kim JK, Lee JS, Cheong JJ, Choi YD. Koo YJ, et al. Plant Mol Biol. 2007 May;64(1-2):1-15. doi: 10.1007/s11103-006-9123-x. Epub 2007 Mar 16. Plant Mol Biol. 2007. PMID: 17364223
A recombinant OsBSMT1 protein obtained by expressing the gene in Escherichia coli exhibited carboxyl methyltransferase activity in reactions with salicylic acid (SA), benzoic acid (BA), and de-S-methyl benzo(1,2,3)thiadiazole-7-carbothioic acid (dSM-BTH), producing methyl …
A recombinant OsBSMT1 protein obtained by expressing the gene in Escherichia coli exhibited carboxyl methyltransferase activity in reactions …
12 results