A Retrospective Analysis of the 1-Year Graft Survival Rate in Indonesian Renal Transplant Recipients With Multiple Renal Arteries

Transplant Proc. 2023 Dec;55(10):2414-2418. doi: 10.1016/j.transproceed.2023.09.021. Epub 2023 Nov 8.

Abstract

Background: Renal transplantation is the preferred treatment for end-stage renal disease because of its association with improved survival and quality of life. The debate over multiple renal arteries (MRA) vs a single renal artery regarding kidney function, posttransplant complications, and graft and patient survival remains ongoing. Our goal was to determine the 1-year graft survival rate among renal transplant recipients with MRA at Cipto Mangunkusumo Hospital in Jakarta.

Methods: A retrospective study was conducted between January 2012 and December 2020, including all kidney transplant candidates with MRA. Data on graft survival, patient demographics, previous renal transplantation, duration of hemodialysis, and delayed graft function were collected and analyzed using SPSS 24. Kaplan-Meier plots and Cox regression analyses were used to determine risk factors for 1-year survival.

Results: Among 752 renal transplant recipients, 104 cases had MRA. The majority were men (71.5%), and the median age of recipients was 47 years. One-year graft survival was observed in 96% of cases, whereas patient survival was 97.7%. No significant difference was found in graft survival based on the number of arteries (single renal artery vs MRA), length of hemodialysis, or previous renal transplantation. However, delayed graft function was significantly associated with graft survival.

Conclusion: This study highlights that 1-year graft survival in renal transplant recipients with MRA is not significantly affected by the length of hemodialysis before surgery or previous renal transplantation.

MeSH terms

  • Delayed Graft Function / etiology
  • Female
  • Graft Survival
  • Humans
  • Indonesia
  • Kidney / blood supply
  • Kidney Diseases* / etiology
  • Kidney Transplantation* / adverse effects
  • Male
  • Middle Aged
  • Quality of Life
  • Renal Artery / surgery
  • Retrospective Studies
  • Survival Rate
  • Transplant Recipients
  • Treatment Outcome
  • Ureteral Diseases* / etiology