Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review).
Banno K, Kisu I, Yanokura M, Tsuji K, Masuda K, Ueki A, Kobayashi Y, Yamagami W, Nomura H, Tominaga E, Susumu N, Aoki D.
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Int J Oncol. 2012 Sep;41(3):793-7. doi: 10.3892/ijo.2012.1528. Epub 2012 Jun 25.
Int J Oncol. 2012.
PMID: 22735547
Free PMC article.
Review.
Epimutation is defined as abnormal transcriptional repression of active genes and/or abnormal activation of usually repressed genes caused by errors in epigenetic gene repression. Epimutation arises in somatic cells and the germline, and constitutional epimutation may also …
Epimutation is defined as abnormal transcriptional repression of active genes and/or abnormal activation of usually repressed genes caused b …