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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1868 1
1885 1
1887 3
1936 1
1937 1
1947 1
1948 2
1949 2
1950 6
1951 3
1952 6
1953 3
1954 6
1955 5
1956 4
1957 4
1958 4
1959 8
1960 3
1961 5
1962 1
1963 8
1964 15
1965 17
1966 17
1967 33
1968 26
1969 33
1970 30
1971 21
1972 26
1973 17
1974 21
1975 53
1976 75
1977 60
1978 61
1979 75
1980 70
1981 84
1982 75
1983 91
1984 83
1985 129
1986 116
1987 128
1988 134
1989 187
1990 156
1991 217
1992 239
1993 200
1994 217
1995 273
1996 263
1997 262
1998 286
1999 289
2000 241
2001 279
2002 326
2003 292
2004 304
2005 350
2006 385
2007 341
2008 347
2009 363
2010 412
2011 457
2012 549
2013 594
2014 600
2015 636
2016 670
2017 686
2018 755
2019 860
2020 968
2021 1009
2022 1073
2023 1032
2024 453

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16,606 results

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Page 1
Review of Treatment for Adenosine Deaminase Deficiency (ADA) Severe Combined Immunodeficiency (SCID).
Secord E, Hartog NL. Secord E, et al. Ther Clin Risk Manag. 2022 Sep 22;18:939-944. doi: 10.2147/TCRM.S350762. eCollection 2022. Ther Clin Risk Manag. 2022. PMID: 36172599 Free PMC article. Review.
The most complete form of ADA leads to severe combined immune deficiency (SCID). Treatment with enzyme replacement therapy (ERT) was developed in the 1970s and became the treatment for ADA SCID by the 1980s. ...This review covers the history of ADA SCID, the …
The most complete form of ADA leads to severe combined immune deficiency (SCID). Treatment with enzyme replacement therapy (ERT) was …
Immunogenicity of TNF-Inhibitors.
Atiqi S, Hooijberg F, Loeff FC, Rispens T, Wolbink GJ. Atiqi S, et al. Front Immunol. 2020 Feb 26;11:312. doi: 10.3389/fimmu.2020.00312. eCollection 2020. Front Immunol. 2020. PMID: 32174918 Free PMC article. Review.
Retrospectively, we recognize this has led to an underestimation of the amount of ADA produced due to drug interference. Drug-tolerant ADA assays also detect ADA in the presence of drug, which has contributed to the currently reported higher incidence of A …
Retrospectively, we recognize this has led to an underestimation of the amount of ADA produced due to drug interference. Drug-toleran …
Comparison of elapegademase and pegademase in ADA-deficient patients and mice.
Murguia-Favela L, Min W, Loves R, Leon-Ponte M, Grunebaum E. Murguia-Favela L, et al. Clin Exp Immunol. 2020 May;200(2):176-184. doi: 10.1111/cei.13420. Epub 2020 Feb 9. Clin Exp Immunol. 2020. PMID: 31989577 Free PMC article.
ADA activity and thymus reconstitution were evaluated in ADA-deficient mice following ELA-ADA or ADAGEN administered from 7 days postpartum. In vitro, ADA activity of ELA-ADA and ADAGEN were similar at all dilutions. ...
ADA activity and thymus reconstitution were evaluated in ADA-deficient mice following ELA-ADA or ADAGEN administered fr …
Adenosine deaminase: functional implications and different classes of inhibitors.
Cristalli G, Costanzi S, Lambertucci C, Lupidi G, Vittori S, Volpini R, Camaioni E. Cristalli G, et al. Med Res Rev. 2001 Mar;21(2):105-28. doi: 10.1002/1098-1128(200103)21:2<105::aid-med1002>3.0.co;2-u. Med Res Rev. 2001. PMID: 11223861 Review.
However, despite a number of studies performed to date, the physiological role played by ADA in the different tissues is not clear. Inherited ADA deficiency causes severe combined immunodeficiency disease (ADA-SCID), in which both B-cell and T-cell developmen …
However, despite a number of studies performed to date, the physiological role played by ADA in the different tissues is not clear. I …
5. Lifestyle Management: Standards of Medical Care in Diabetes-2019.
American Diabetes Association. American Diabetes Association. Diabetes Care. 2019 Jan;42(Suppl 1):S46-S60. doi: 10.2337/dc19-S005. Diabetes Care. 2019. PMID: 30559231 Review.
The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality …
The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recom …
Metabolite and thymocyte development defects in ADA-SCID mice receiving enzyme replacement therapy.
Moretti FA, Giardino G, Attenborough TCH, Gkazi AS, Margetts BK, la Marca G, Fairbanks L, Crompton T, Gaspar HB. Moretti FA, et al. Sci Rep. 2021 Dec 1;11(1):23221. doi: 10.1038/s41598-021-02572-w. Sci Rep. 2021. PMID: 34853379 Free PMC article.
Administration of ERT in the form of pegylated bovine ADA (PEG-ADA) has proved a life-saving though non-curative treatment for ADA-SCID patients. ...Here, we show reduced thymus cellularity in ADA-SCID mice despite weekly PEG-ADA treatment. This …
Administration of ERT in the form of pegylated bovine ADA (PEG-ADA) has proved a life-saving though non-curative treatment for …
The Immunogenicity of Biologic Therapies.
Garcês S, Demengeot J. Garcês S, et al. Curr Probl Dermatol. 2018;53:37-48. doi: 10.1159/000478077. Epub 2017 Nov 7. Curr Probl Dermatol. 2018. PMID: 29131036
The detection of ADA is technically challenging and all assays have limitations, namely a limited capacity in detecting ADA in the presence of a drug due to immune complex (IC) formation, which may underestimate the ADA incidence. Refined assays, able to disr …
The detection of ADA is technically challenging and all assays have limitations, namely a limited capacity in detecting ADA in …
ADA Deficiency: Evaluation of the Clinical and Laboratory Features and the Outcome.
Cagdas D, Gur Cetinkaya P, Karaatmaca B, Esenboga S, Tan C, Yılmaz T, Gümüş E, Barış S, Kuşkonmaz B, Ozgur TT, Bali P, Santisteban I, Orhan D, Yüce A, Cetinkaya D, Boztug K, Hershfield M, Sanal O, Tezcan İ. Cagdas D, et al. J Clin Immunol. 2018 May;38(4):484-493. doi: 10.1007/s10875-018-0496-9. Epub 2018 May 9. J Clin Immunol. 2018. PMID: 29744787
METHODS: Measurement of ADA enzyme activity and metabolites and sequencing of the ADA gene were performed in most of the patients with ADA deficiency. ...Eight patients with ADA-SCID were found to have higher levels of ADA metabolite (dAXP%) (62 …
METHODS: Measurement of ADA enzyme activity and metabolites and sequencing of the ADA gene were performed in most of the patie …
Diagnosis of tuberculosis pleurisy with adenosine deaminase (ADA): a systematic review and meta-analysis.
Gui X, Xiao H. Gui X, et al. Int J Clin Exp Med. 2014 Oct 15;7(10):3126-35. eCollection 2014. Int J Clin Exp Med. 2014. PMID: 25419343 Free PMC article. Review.
Thus, ADA is a relatively sensitive and specific marker for tuberculosis pleurisy diagnosis. ...Further studies are required to confirm the optimal cut-off value of ADA....
Thus, ADA is a relatively sensitive and specific marker for tuberculosis pleurisy diagnosis. ...Further studies are required to confi …
Age : pleural fluid ADA ratio and other indicators for differentiating between tubercular and malignant pleural effusions.
Zhou J, Yang Y, Zhang Y, Liu H, Dou Q. Zhou J, et al. Medicine (Baltimore). 2022 Jul 1;101(26):e29788. doi: 10.1097/MD.0000000000029788. Medicine (Baltimore). 2022. PMID: 35777003 Free PMC article.
The areas under the curve (AUC) of age/ADA and pleural fluid ADA were largest. Age/ADA showed sensitivity and specificity of 81.5% (95%CI 73.8%-87.8%) and 97.8% (95%CI 92.2%-99.7%) respectively. ...The diagnostic accuracy of Cancer Ratio and Cancer Ratio plus …
The areas under the curve (AUC) of age/ADA and pleural fluid ADA were largest. Age/ADA showed sensitivity and specifici …
16,606 results
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