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Edible mushrooms as potential functional foods in amelioration of hypertension.
Rauf A, Joshi PB, Ahmad Z, Hemeg HA, Olatunde A, Naz S, Hafeez N, Simal-Gandara J. Rauf A, et al. Phytother Res. 2023 Jun;37(6):2644-2660. doi: 10.1002/ptr.7865. Epub 2023 May 8. Phytother Res. 2023. PMID: 37157920 Review.
Edible mushrooms are omnipresent in various prescribed Dietary Approaches to Stop Hypertension, Mediterranean diet, and fortified meal plans as they are rich in amino acids, dietary fiber, proteins, sterols, vitamins, and minerals. ...
Edible mushrooms are omnipresent in various prescribed Dietary Approaches to Stop Hypertension, Mediterranean diet, and fortified meal plans …
The medicinal chemistry of Urtica dioica L.: from preliminary evidence to clinical studies supporting its neuroprotective activity.
Semwal P, Rauf A, Olatunde A, Singh P, Zaky MY, Islam MM, Khalil AA, Aljohani ASM, Al Abdulmonem W, Ribaudo G. Semwal P, et al. Nat Prod Bioprospect. 2023 May 12;13(1):16. doi: 10.1007/s13659-023-00380-5. Nat Prod Bioprospect. 2023. PMID: 37171512 Free PMC article. Review.
In this connection, bioactive chemical constituents such as flavonoids, phenolic acids, amino acids, carotenoids, and fatty acids have been isolated from the plant. ...
In this connection, bioactive chemical constituents such as flavonoids, phenolic acids, amino acids, carotenoids, and fatty acids hav …
Genomic and In Vitro Phenotypic Comparisons of Epidemic and Non-Epidemic Getah Virus Strains.
Mohamed-Romai-Noor NA, Sam SS, Teoh BT, Hamim ZR, AbuBakar S. Mohamed-Romai-Noor NA, et al. Viruses. 2022 Apr 30;14(5):942. doi: 10.3390/v14050942. Viruses. 2022. PMID: 35632684 Free PMC article.
Our complete coding genome sequence analyses revealed several amino acid substitutions unique to the GETV GIII and GIV groups, which were found mainly in the hypervariable domain of nsP3 and E2 proteins. ...
Our complete coding genome sequence analyses revealed several amino acid substitutions unique to the GETV GIII and GIV groups, which …
The phytochemical and anti-inflammatory studies of Dillenia suffruticosa leaves.
Abubakar S, Al-Mansoub MA, Murugaiyah V, Chan KL. Abubakar S, et al. Phytother Res. 2019 Mar;33(3):660-675. doi: 10.1002/ptr.6255. Epub 2019 Jan 17. Phytother Res. 2019. PMID: 30653753
The in silico molecular docking studies provided support to the in vitro COX studies that the isolated compounds formed H-bonding with the amino acid residues at the COX-2 catalytic sites. The triterpenoids were bound to the peroxidase, possibly inhibiting the peroxidase r …
The in silico molecular docking studies provided support to the in vitro COX studies that the isolated compounds formed H-bonding with the …
Defective functions of HNF1A variants on BCL2L1 transactivation and beta-cell growth.
Sujjitjoon J, Charoensuk C, Thanyaphon T, Kooptiwut S, Thamtarana PJ, Tangjittipokin W, Chongjaroen N, Chanprasert C, Abubakar Z, Lapbenjakul S, Yenchitsomanus PT, Plengvidhya N. Sujjitjoon J, et al. Biochem Biophys Res Commun. 2020 Aug 27;529(3):826-833. doi: 10.1016/j.bbrc.2020.05.155. Epub 2020 Jul 17. Biochem Biophys Res Commun. 2020. PMID: 32684311
Analysis of BnMTL, a novel metallothionein-like protein in the bast fiber crop Ramie (Boehmeria nivea).
Gao G, Chen J, Chen P, Chen K, Abubakar AS, Yu C, Zhu A. Gao G, et al. FEBS Open Bio. 2019 Sep;9(9):1632-1639. doi: 10.1002/2211-5463.12705. Epub 2019 Aug 18. FEBS Open Bio. 2019. PMID: 31353835 Free PMC article.
In the present study, we cloned a novel metallothionein-like gene from ramie; this gene, termed BnMTL, encodes a putative 46 amino acid protein with a molecular mass of 4.38 kDa. Analysis using quantitative RT-PCR revealed that cadmium (Cd(2+) ) treatment results in elevat …
In the present study, we cloned a novel metallothionein-like gene from ramie; this gene, termed BnMTL, encodes a putative 46 amino ac …
Autosomal dominant diabetes associated with a novel ZYG11A mutation resulting in cell cycle arrest in beta-cells.
Charoensuk C, Thamtarana PJ, Chanprasert C, Tangjittipokin W, Shirakawa J, Togashi Y, Orime K, Songprakhon P, Chaichana C, Abubakar Z, Ouying P, Sujjitjoon J, Doria A, Plengvidhya N, Yenchitsomanus PT. Charoensuk C, et al. Mol Cell Endocrinol. 2021 Feb 15;522:111126. doi: 10.1016/j.mce.2020.111126. Epub 2020 Dec 13. Mol Cell Endocrinol. 2021. PMID: 33321115 Free article.
Molecular characterization of a tsetse fly midgut proteolytic lectin that mediates differentiation of African trypanosomes.
Abubakar LU, Bulimo WD, Mulaa FJ, Osir EO. Abubakar LU, et al. Insect Biochem Mol Biol. 2006 Apr;36(4):344-52. doi: 10.1016/j.ibmb.2006.01.010. Epub 2006 Jan 19. Insect Biochem Mol Biol. 2006. PMID: 16551548
As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and trypsin activities from midguts of the tsetse fly, Glossina longipennis [Osir, E.O., Abubakar, L., Imbuga, M.O., 1995. Purification an …
As part of an on-going project in our laboratory, we recently isolated and characterized a bloodmeal-induced molecule with both lectin and t …
Conformational Design and Characterisation of a Truncated Diamine Oxidase from Arthrobacter globiformis.
Razali NN, Hashim NH, Leow ATC, Salleh AB. Razali NN, et al. High Throughput. 2018 Aug 25;7(3):21. doi: 10.3390/ht7030021. High Throughput. 2018. PMID: 30149644 Free PMC article.
In this study, a huge enzyme molecule, known as diamine oxidase (DAO, comprising 700 amino acids), was selected to undergo the process. By retaining the arrangement of the original functional sites of DAO in the fourth domain, a mini DAO can be designed via homology modell …
In this study, a huge enzyme molecule, known as diamine oxidase (DAO, comprising 700 amino acids), was selected to undergo the proces …
Structural Investigations and Binding Mechanisms of Oseltamivir Drug Resistance Conferred by the E119V Mutation in Influenza H7N9 Virus.
Ugbaja SC, Mtambo SE, Mushebenge AG, Appiah-Kubi P, Abubakar BH, Ntuli ML, Kumalo HM. Ugbaja SC, et al. Molecules. 2022 Jul 8;27(14):4376. doi: 10.3390/molecules27144376. Molecules. 2022. PMID: 35889251 Free PMC article.
The presence of the neuraminidase protein in the avian influenza H7N9 virus and its critical role in the cleavage of sialic acid have made it a target drug in the development of influenza virus drugs. Generally, the neuraminidase proteins have common conserved amino acid r …
The presence of the neuraminidase protein in the avian influenza H7N9 virus and its critical role in the cleavage of sialic acid have made i …
36 results