Coumarin Derivatives Exert Anti-Lung Cancer Activity by Inhibition of Epithelial-Mesenchymal Transition and Migration in A549 Cells.
de Araújo RSA, Carmo JODS, de Omena Silva SL, Costa da Silva CRA, Souza TPM, Mélo NB, Bourguignon JJ, Schmitt M, Aquino TM, Rodarte RS, Moura RO, Barbosa Filho JM, Barreto E, Mendonça-Junior FJB.
de Araújo RSA, et al.
Pharmaceuticals (Basel). 2022 Jan 17;15(1):104. doi: 10.3390/ph15010104.
Pharmaceuticals (Basel). 2022.
PMID: 35056161
Free PMC article.
A series of coumarin derivatives and isosteres were synthesized from the reaction of triflic intermediates with phenylboronic acids, terminal alkynes, and organozinc compounds through palladium-catalyzed cross-coupling reactions. ...
A series of coumarin derivatives and isosteres were synthesized from the reaction of triflic intermediates with phenylboronic acids, termina …