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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1974 1
1976 2
1978 2
1979 1
1980 1
1981 1
1982 2
1983 1
1984 2
1987 5
1988 4
1989 11
1990 14
1991 13
1992 8
1993 12
1994 17
1995 24
1996 28
1997 30
1998 24
1999 18
2000 24
2001 25
2002 28
2003 37
2004 33
2005 39
2006 37
2007 40
2008 38
2009 24
2010 27
2011 42
2012 39
2013 42
2014 51
2015 54
2016 76
2017 67
2018 68
2019 77
2020 88
2021 82
2022 53
2023 54
2024 28

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1,245 results

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Page 1
Targeting DNA binding proteins for cancer therapy.
Shiroma Y, Takahashi RU, Yamamoto Y, Tahara H. Shiroma Y, et al. Cancer Sci. 2020 Apr;111(4):1058-1064. doi: 10.1111/cas.14355. Epub 2020 Mar 24. Cancer Sci. 2020. PMID: 32073717 Free PMC article. Review.
In the present review, we summarize known cancer-associated TFs according to cancer type and introduce recently developed high-throughput approaches to identify selective inhibitors of cancer-associated TFs....
In the present review, we summarize known cancer-associated TFs according to cancer type and introduce recently developed high-throughput ap …
Prolyl isomerase Pin1 in metabolic reprogramming of cancer cells.
Nakatsu Y, Yamamotoya T, Ueda K, Ono H, Inoue MK, Matsunaga Y, Kushiyama A, Sakoda H, Fujishiro M, Matsubara A, Asano T. Nakatsu Y, et al. Cancer Lett. 2020 Feb 1;470:106-114. doi: 10.1016/j.canlet.2019.10.043. Epub 2019 Oct 31. Cancer Lett. 2020. PMID: 31678165 Review.
Development of Pin1 Inhibitors and their Potential as Therapeutic Agents.
Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T. Nakatsu Y, et al. Curr Med Chem. 2020;27(20):3314-3329. doi: 10.2174/0929867325666181105120911. Curr Med Chem. 2020. PMID: 30394205 Review.
In contrast, Pin1 overexpression is highly correlated with the degree of malignancy of cancers, as Pin1 controls a number of oncogenes and tumor suppressors. Accordingly, Pin1 inhibitors as anti-cancer drugs have been developed. Interestingly, recent intensive studies have …
In contrast, Pin1 overexpression is highly correlated with the degree of malignancy of cancers, as Pin1 controls a number of oncogenes and t …
Current status of prognostic factors in patients with metastatic renal cell carcinoma.
Teishima J, Inoue S, Hayashi T, Matsubara A. Teishima J, et al. Int J Urol. 2019 Jun;26(6):608-617. doi: 10.1111/iju.13956. Epub 2019 Apr 8. Int J Urol. 2019. PMID: 30959579 Review.
In recent years, the induction of novel agents, including molecular-targeted agents and immune checkpoint inhibitors, have dramatically changed therapeutic options and their outcomes for metastatic renal cell carcinoma. ...
In recent years, the induction of novel agents, including molecular-targeted agents and immune checkpoint inhibitors, have dramatical …
Molecular mechanisms of environmental organotin toxicity in mammals.
Kotake Y. Kotake Y. Biol Pharm Bull. 2012;35(11):1876-80. doi: 10.1248/bpb.b212017. Biol Pharm Bull. 2012. PMID: 23123459 Free article. Review.
In this review, we summarize recent findings on the mechanisms of toxicity of environmental organotins such as tributyltin (TBT) and triphenyltin (TPT) in mammals. TBT and TPT are potent inhibitors of mitochondrial ATP synthase, and a recent study suggests that TBT binds d …
In this review, we summarize recent findings on the mechanisms of toxicity of environmental organotins such as tributyltin (TBT) and triphen …
1,245 results