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Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells.
Bunik VI, Denton TT, Xu H, Thompson CM, Cooper AJ, Gibson GE. Bunik VI, et al. Biochemistry. 2005 Aug 9;44(31):10552-61. doi: 10.1021/bi0503100. Biochemistry. 2005. PMID: 16060664
Previous studies showed that succinyl phosphonate (SP) effectively inhibits muscle and Escherichia coli KGDHC [Biryukov, A. I., Bunik, V. I., Zhukov, Yu. N., Khurs, E. N., and Khomutov, R. ...
Previous studies showed that succinyl phosphonate (SP) effectively inhibits muscle and Escherichia coli KGDHC [Biryukov, A. I., Bunik …
The rLVS deltacapB/iglABC vaccine provides potent protection in Fischer rats against inhalational tularemia caused by various virulent Francisella tularensis strains.
Mlynek KD, Cline CR, Biryukov SS, Toothman RG, Bachert BA, Klimko CP, Shoe JL, Hunter M, Hedrick ZM, Dankmeyer JL, Mou S, Fetterer DP, Qiu J, Lee ED, Cote CK, Jia Q, Horwitz MA, Bozue JA. Mlynek KD, et al. Hum Vaccin Immunother. 2023 Dec 15;19(3):2277083. doi: 10.1080/21645515.2023.2277083. Epub 2023 Nov 17. Hum Vaccin Immunother. 2023. PMID: 37975637 Free PMC article.
The rats were exposed to a high dose of aerosolized Type A strain Schu S4 (FRAN244), a Type B strain (FRAN255), or a tick derived Type A strain (FRAN254) and monitored for survival. ...Against the Type B strain, two doses of 10(7) CFU rLVS provided 100% protection, and a s …
The rats were exposed to a high dose of aerosolized Type A strain Schu S4 (FRAN244), a Type B strain (FRAN255), or a tick derived Typ …
Lecithin Prevents Cortical Cytoskeleton Reorganization in Rat Soleus Muscle Fibers under Short-Term Gravitational Disuse.
Ogneva IV, Biryukov NS. Ogneva IV, et al. PLoS One. 2016 Apr 13;11(4):e0153650. doi: 10.1371/journal.pone.0153650. eCollection 2016. PLoS One. 2016. PMID: 27073851 Free PMC article.
The aim of this study was to prevent the cortical cytoskeleton reorganization of rat soleus muscle fibers under short-term gravitational disuse. Once a day, we injected the right soleus muscle with 0.5 ml lecithin at a concentration of 200 mg/ml and the left soleus muscle …
The aim of this study was to prevent the cortical cytoskeleton reorganization of rat soleus muscle fibers under short-term gravitatio …
Possible role of non-muscle alpha-actinins in muscle cell mechanosensitivity.
Ogneva IV, Biryukov NS, Leinsoo TA, Larina IM. Ogneva IV, et al. PLoS One. 2014 Apr 29;9(4):e96395. doi: 10.1371/journal.pone.0096395. eCollection 2014. PLoS One. 2014. PMID: 24780915 Free PMC article.
The study subjects were fibers of the soleus muscle and cardiomyocytes of Wistar rats. Changes in external mechanical conditions were reconstructed by means of antiorthostatic suspension of the animals by their tails for 6, 12, 18, 24 and 72 hours. ...
The study subjects were fibers of the soleus muscle and cardiomyocytes of Wistar rats. Changes in external mechanical conditions were …
Structure and functional characteristics of rat's left ventricle cardiomyocytes under antiorthostatic suspension of various duration and subsequent reloading.
Ogneva IV, Mirzoev TM, Biryukov NS, Veselova OM, Larina IM. Ogneva IV, et al. J Biomed Biotechnol. 2012;2012:659869. doi: 10.1155/2012/659869. Epub 2012 Oct 2. J Biomed Biotechnol. 2012. PMID: 23093854 Free PMC article.
The goal of the research was to identify the structural and functional characteristics of the rat's left ventricle under antiorthostatic suspension within 1, 3, 7 and 14 days, and subsequent 3 and 7-day reloading after a 14-day suspension. ...
The goal of the research was to identify the structural and functional characteristics of the rat's left ventricle under antiorthosta …