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1955 3
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1958 2
1959 9
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1968 17
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The following term was not found in PubMed: Zong-fu
Page 1
Did you mean zang fu fu (783 results)?
5-FU Cardiotoxicity: Vasospasm, Myocarditis, and Sudden Death.
More LA, Lane S, Asnani A. More LA, et al. Curr Cardiol Rep. 2021 Feb 3;23(3):17. doi: 10.1007/s11886-021-01441-2. Curr Cardiol Rep. 2021. PMID: 33537861 Review.
PURPOSE OF REVIEW: 5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. ...Here we summarize the mechanistic and clinical data available to guide clinicians in caring for patients with suspected 5-FU cardiotoxicity. …
PURPOSE OF REVIEW: 5-fluorouracil (5-FU) is one of the most common causes of cardiotoxicity associated with chemotherapy. ...Here we …
Use of Topical Calcipotriol Plus 5-Fluorouracil in the Treatment of Actinic Keratosis: A Systematic Review.
Mohney L, Singh R, Grada A, Feldman S. Mohney L, et al. J Drugs Dermatol. 2022 Jan 1;21(1):60-65. doi: 10.36849/JDD.2022.6632. J Drugs Dermatol. 2022. PMID: 35005863
One clinical trial evaluated the efficacy of calcipotriol plus 5-FU in treating AK. Another clinical trial evaluated the long-term effect of calcipotriol plus 5-FU in prevention of cSCC. ...The active control arm (Petroleum jelly plus 5-FU combination) is not …
One clinical trial evaluated the efficacy of calcipotriol plus 5-FU in treating AK. Another clinical trial evaluated the long-term ef …
KLF4 targets RAB26 and decreases 5-FU resistance through inhibiting autophagy in colon cancer.
Zheng Y, Wu J, Chen H, Lin D, Chen H, Zheng J, Xia H, Huang L, Zeng C. Zheng Y, et al. Cancer Biol Ther. 2023 Dec 31;24(1):2226353. doi: 10.1080/15384047.2023.2226353. Cancer Biol Ther. 2023. PMID: 37431852 Free PMC article.
BACKGROUND: Accumulating studies demonstrated that resistance of colon cancer (CC) to 5-fluorouracil (5-FU) contributes to adverse prognosis. We investigated how Kruppel-like factor 4 (KLF4) affected 5-FU resistance and autophagy in CC cells. ...Autophagy activator …
BACKGROUND: Accumulating studies demonstrated that resistance of colon cancer (CC) to 5-fluorouracil (5-FU) contributes to adverse pr …
Review of 5-FU resistance mechanisms in colorectal cancer: clinical significance of attenuated on-target effects.
Gmeiner WH, Okechukwu CC. Gmeiner WH, et al. Cancer Drug Resist. 2023 Apr 29;6(2):257-272. doi: 10.20517/cdr.2022.136. eCollection 2023. Cancer Drug Resist. 2023. PMID: 37457133 Free PMC article. Review.
The causes of 5-FU resistance are multi-factorial, and besides DNA mismatch repair deficiency (MMR-D), there are no widely accepted criteria for determining which CRC patients are not likely to be responsive to 5-FU-based therapy. Thus, there is a need to systematic …
The causes of 5-FU resistance are multi-factorial, and besides DNA mismatch repair deficiency (MMR-D), there are no widely accepted c …
ERRATUM.
Furutani A, Sowa Y, Fujiwara H, Otsuji E, Sakai T. Furutani A, et al. Oncol Res. 2016 Jan 21;23(1):87. doi: 10.3727/096504016X14514194509664. Oncol Res. 2016. PMID: 29021025 Free PMC article.
Histone deacetylase (HDAC) inhibitors have been shown to enhance the effects of 5-fluorouracil (5-FU) against various cancer cells; however, no report has shown that an HDAC inhibitor may enhance the effects of 5-FU with radiation. ...The inhibition of the cell grow …
Histone deacetylase (HDAC) inhibitors have been shown to enhance the effects of 5-fluorouracil (5-FU) against various cancer cells; h …
How can we best monitor 5-FU administration to maximize benefit to risk ratio?
Goirand F, Lemaitre F, Launay M, Tron C, Chatelut E, Boyer JC, Bardou M, Schmitt A. Goirand F, et al. Expert Opin Drug Metab Toxicol. 2018 Dec;14(12):1303-1313. doi: 10.1080/17425255.2018.1550484. Epub 2018 Nov 23. Expert Opin Drug Metab Toxicol. 2018. PMID: 30451549 Free article. Review.
5-Fluorouracil (5-FU) is currently used as a chemotherapy in several cancers such as head-and-neck (H&N) and colorectal cancers. 5-FU dosing is traditionally based on body surface area (BSA), but this strategy is usually associated with severe toxicities. 5-F
5-Fluorouracil (5-FU) is currently used as a chemotherapy in several cancers such as head-and-neck (H&N) and colorectal cancers. …
Should we still be using bolus 5-FU prior to infusional regimens in gastrointestinal cancers? A practical review.
Amorim LC, Peixoto RD. Amorim LC, et al. Int Cancer Conf J. 2021 Nov 24;11(1):2-5. doi: 10.1007/s13691-021-00526-7. eCollection 2022 Jan. Int Cancer Conf J. 2021. PMID: 35127313 Free PMC article. Review.
The true clinical value of bolus 5-FU right before infusional regimens remains to be determined since no randomized trials have addressed this issue. This manuscript aims to review the history of 5-FU, its mechanism of action and the data exploring the role of bolus …
The true clinical value of bolus 5-FU right before infusional regimens remains to be determined since no randomized trials have addre …
SPOCK1 silencing decreases 5-FU resistance through PRRX1 in colorectal cancer.
Qu YL, Liu XL, Zhao SY, Zhai XF. Qu YL, et al. Pathol Res Pract. 2022 Jun;234:153895. doi: 10.1016/j.prp.2022.153895. Epub 2022 Apr 12. Pathol Res Pract. 2022. PMID: 35462225
However, the relationship between development of resistance to 5-FU and SPOCK1 remain unclear. In this study, we established two 5-fluorouracil (5-FU)-resistant CRC cell lines, HCT116/FU and LOVO/FU, and found that SPOCK1 is upregulated in 5-FU- …
However, the relationship between development of resistance to 5-FU and SPOCK1 remain unclear. In this study, we established two 5-fl …
Biochemical modulation of 5-FU in systemic treatment of advanced colorectal cancer.
Grem JL. Grem JL. Oncology (Williston Park). 2001 Jan;15(1 Suppl 2):13-9. Oncology (Williston Park). 2001. PMID: 11219972 Review.
Sequential methotrexate followed by i.v. bolus 5-FU is associated with a higher response rate. Continuous infusion schedules also produce superior response rates compared to bolus 5-FU alone. Published meta-analyses indicate a small, but statistically significant, s …
Sequential methotrexate followed by i.v. bolus 5-FU is associated with a higher response rate. Continuous infusion schedules also pro …
Therapeutic drug monitoring of 5-fluorouracil.
Lee JJ, Beumer JH, Chu E. Lee JJ, et al. Cancer Chemother Pharmacol. 2016 Sep;78(3):447-64. doi: 10.1007/s00280-016-3054-2. Epub 2016 May 23. Cancer Chemother Pharmacol. 2016. PMID: 27217046 Free PMC article. Review.
However, it is now well established that BSA-based 5-FU dosing is correlated with a wide variation of 5-FU systemic exposure. ...There is growing evidence to show that 5-FU dosing based on plasma 5-FU drug level is feasible and that 5-FU TDM can …
However, it is now well established that BSA-based 5-FU dosing is correlated with a wide variation of 5-FU systemic exposure. …
181,397 results
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