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893 results

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Page 1
Showing results for zhang phe gov
Search for Zhang-He Goh instead (1 results)
A noncoding RNA modulator potentiates phenylalanine metabolism in mice.
Li Y, Tan Z, Zhang Y, Zhang Z, Hu Q, Liang K, Jun Y, Ye Y, Li YC, Li C, Liao L, Xu J, Xing Z, Pan Y, Chatterjee SS, Nguyen TK, Hsiao H, Egranov SD, Putluri N, Coarfa C, Hawke DH, Gunaratne PH, Tsai KL, Han L, Hung MC, Calin GA, Namour F, Guéant JL, Muntau AC, Blau N, Sutton VR, Schiff M, Feillet F, Zhang S, Lin C, Yang L. Li Y, et al. Science. 2021 Aug 6;373(6555):662-673. doi: 10.1126/science.aba4991. Science. 2021. PMID: 34353949 Free PMC article.
Here, we demonstrate that the mouse lncRNA Pair and human HULC associate with phenylalanine hydroxylase (PAH). Pair-knockout mice exhibited excessive blood phenylalanine (Phe), musty odor, hypopigmentation, growth retardation, and progressive neurological symptoms includin …
Here, we demonstrate that the mouse lncRNA Pair and human HULC associate with phenylalanine hydroxylase (PAH). Pair-knockout mice exhibited …
Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage.
Li Z, Li M, Shi SX, Yao N, Cheng X, Guo A, Zhu Z, Zhang X, Liu Q. Li Z, et al. J Exp Med. 2020 Dec 7;217(12):e20200213. doi: 10.1084/jem.20200213. J Exp Med. 2020. PMID: 32870258 Free PMC article.
Perihematomal edema (PHE) occurs within hours after intracerebral hemorrhage (ICH), leading to secondary injury manifested by impaired blood-brain barrier (BBB) integrity and destruction of adjacent tissue. ...Thus, brain-bound NK cells acquire new features that contribute …
Perihematomal edema (PHE) occurs within hours after intracerebral hemorrhage (ICH), leading to secondary injury manifested by impaire …
(64)Cu-[cinnamoyl-Phe-D-Leu-Phe-D-Leu-Phe-Lys(PEG-1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid)-NH(2)].
Chopra A, Pan D. Chopra A, et al. 2007 Nov 1 [updated 2008 May 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2007 Nov 1 [updated 2008 May 30]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641543 Free Books & Documents. Review.
However, although these compounds show promise, they have undesirable side effects because they either activate neutrophils, which results in neutropenia or demargination, have a low retention at the target site, or show low affinity for the receptor (5, 6). Zhang et al. e …
However, although these compounds show promise, they have undesirable side effects because they either activate neutrophils, which results i …
CLIO-(H-2K(d))-Lys-Tyr-Asp-Lys-Ala-Asp-Val-Phe-Leu.
Zhang H. Zhang H. 2008 Aug 15 [updated 2008 Sep 16]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Aug 15 [updated 2008 Sep 16]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641772 Free Books & Documents. Review.
Thus, IGRP has been used as a target for human diabetogenic response. NOD peptide (NRP-V7) (Lys-Tyr-Asp-Lys-Ala-Asp-Val-Phe-Leu (KYNKANVEL)) is a mimotope of IGRP that shares a 67% sequence homology with the endogenous IGRP(206-214) epitope and has high avidity for H-2K(d) …
Thus, IGRP has been used as a target for human diabetogenic response. NOD peptide (NRP-V7) (Lys-Tyr-Asp-Lys-Ala-Asp-Val-Phe-Leu (KYNK …
Π-Clamp-mediated cysteine conjugation.
Zhang C, Welborn M, Zhu T, Yang NJ, Santos MS, Van Voorhis T, Pentelute BL. Zhang C, et al. Nat Chem. 2016 Feb;8(2):120-8. doi: 10.1038/nchem.2413. Epub 2015 Dec 21. Nat Chem. 2016. PMID: 26791894 Free PMC article.
Typically, protecting groups or catalysts must be used to enable the selective modification of one site among many that are similarly reactive, and general strategies that selectively tune the local chemical environment around a target site are rare. Here, we show a four-amino-ac …
Typically, protecting groups or catalysts must be used to enable the selective modification of one site among many that are similarly reacti …
Anti-osteoporotic drugs affect the pathogenesis of gut microbiota and its metabolites: a clinical study.
Zhang RK, Yan K, Chen HF, Zhang Y, Li GJ, Chen XG, Ge LP, Cheng F, Chen ZN, Yao XM. Zhang RK, et al. Front Cell Infect Microbiol. 2023 Jul 4;13:1091083. doi: 10.3389/fcimb.2023.1091083. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37475958 Free PMC article. Clinical Trial.
The metabolites for which major changes were observed were capsazepine, Phe-Tyr, dichlorprop, D-pyroglutamic acid and tamsulosin. These metabolites may act through metabolic pathways, the citrate cycle (TCA cycle) and beta alanine metabolism. ...
The metabolites for which major changes were observed were capsazepine, Phe-Tyr, dichlorprop, D-pyroglutamic acid and tamsulosin. The …
Prognostic significance of perihematomal edema in basal ganglia hemorrhage after minimally invasive endoscopic evacuation.
Wu X, Liu H, Zhang R, Du Y, Cai Y, Tan Z, Liu F, Gao F, Zhang H, Zhou G, Sun F, Fan R, Wang P, Wang L, Ge S, Zhao T, Xie G, Li D, Qu Y, Guo W. Wu X, et al. J Neurosurg. 2023 May 19;139(6):1784-1791. doi: 10.3171/2023.4.JNS222910. Print 2023 Dec 1. J Neurosurg. 2023. PMID: 37209077

Specifically, patients with large ( 50 to < 75 ml) and extra-large ( 75 to 100 ml) postoperative PHE volumes had 4.61 (95% CI 0.99-21.53) and 6.75 (95% CI 1.20-37.85) times greater likelihood of long-term dependence, respectively, than patients with a small postoperativ

Specifically, patients with large ( 50 to < 75 ml) and extra-large ( 75 to 100 ml) postoperative PHE volumes had 4.61 (95% CI 0.99

Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-kappaB and SOX5/PI3K/AKT pathways.
Cai J, Liang J, Zhang Y, Shen L, Lin H, Hu T, Zhan S, Xie M, Liang S, Xian M, Wang S. Cai J, et al. Pharmacol Res. 2022 Jun;180:106230. doi: 10.1016/j.phrs.2022.106230. Epub 2022 Apr 25. Pharmacol Res. 2022. PMID: 35483515
Hence, it is imperative to find new and effective drugs for modulating microglia to treat IR brain injury. Cyclic peptide compound cyclo-(Phe-Tyr) (Sparganin C, SC) is a compound isolated from Sparganii Rhizoma. ...
Hence, it is imperative to find new and effective drugs for modulating microglia to treat IR brain injury. Cyclic peptide compound cyclo-( …
Cbz-Phe-Lys(Cy5)-methyl ketone-2,6,dimethylterephthalic amide-hexyl-QSY 21.
Zhang H. Zhang H. 2008 Nov 24 [updated 2009 Jan 5]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Nov 24 [updated 2009 Jan 5]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641588 Free Books & Documents. Review.
With an optical labeling as the tag, the ABPs can be used to image the activity of proteolytic enzymes in vivo (1). CBz-Phe-Lys(Cy5)-methyl ketone-2,6,dimethylterephthalic amide-hexyl-QSY 21(GB137) is an optical agent used for imaging cysteine cathepsins in vivo (1). ...
With an optical labeling as the tag, the ABPs can be used to image the activity of proteolytic enzymes in vivo (1). CBz-Phe-Lys(Cy5)- …
Disability weight measurement for the severity of different diseases in Wuhan, China.
Liu X, Guo Y, Wang F, Yu Y, Yan Y, Wen H, Shi F, Wang Y, Wang X, Shen H, Li S, Gong Y, Ke S, Zhang W, Jin Q, Zhang G, Wu Y, Zhou M, Yu C. Liu X, et al. Popul Health Metr. 2023 May 4;21(1):5. doi: 10.1186/s12963-023-00304-y. Popul Health Metr. 2023. PMID: 37143047 Free PMC article.
Based on GBD 2013 DW study, paired comparison (PC) and Population health equivalence (PHE) method was used and different PC/PHE questions were randomly assigned to each respondent. ...The probit regression results will be anchored by results from the PHE data …
Based on GBD 2013 DW study, paired comparison (PC) and Population health equivalence (PHE) method was used and different PC/PHE
893 results