Hydrogen-bonded multilayer of pH-responsive polymeric micelles with tannic acid for surface drug delivery

Chem Commun (Camb). 2009 Jul 28:(28):4194-6. doi: 10.1039/b908688a. Epub 2009 Jun 16.

Abstract

We report the design of a platform for the delivery of hydrophobic drugs conjugated to block copolymer micelles via pH-responsive linkage that are assembled within hydrogen-bonded polymer multilayer thin films.

MeSH terms

  • Drug Carriers*
  • HeLa Cells
  • Humans
  • Hydrogen Bonding*
  • Hydrogen-Ion Concentration*
  • Micelles*
  • Microscopy, Atomic Force
  • Polymers / chemistry*
  • Tannins / chemistry*

Substances

  • Drug Carriers
  • Micelles
  • Polymers
  • Tannins