A Knock-In Mouse Model of Thymoma With the GTF2I L424H Mutation.
He Y, Kim IK, Bian J, Polyzos A, Di Giammartino DC, Zhang YW, Luo J, Hernandez MO, Kedei N, Cam M, Borczuk AC, Lee T, Han Y, Conner EA, Wong M, Tillo DC, Umemura S, Chen V, Ruan L, White JB, Miranda IC, Awasthi PP, Altorki NK, Divakar P, Elemento O, Apostolou E, Giaccone G.
He Y, et al. Among authors: kim ik.
J Thorac Oncol. 2022 Dec;17(12):1375-1386. doi: 10.1016/j.jtho.2022.08.008. Epub 2022 Aug 30.
J Thorac Oncol. 2022.
PMID: 36049655
Free PMC article.
RESULTS: We observed that the Gtf2i mutation impairs development of the thymic medulla and maturation of medullary thymic epithelial cells in young mice and causes tumor formation in the thymus of aged mice. ...
RESULTS: We observed that the Gtf2i mutation impairs development of the thymic medulla and maturation of medullary thymic epithelial cells i …