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2013 1
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Page 1
Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations.
Varkaris A, Fece de la Cruz F, Martin EE, Norden BL, Chevalier N, Kehlmann AM, Leshchiner I, Barnes H, Ehnstrom S, Stavridi AM, Yuan X, Kim JS, Ellis H, Papatheodoridi A, Gunaydin H, Danysh BP, Parida L, Sanidas I, Ji Y, Lau K, Wulf GM, Bardia A, Spring LM, Isakoff SJ, Lennerz JK, Del Vecchio K, Pierce L, Pazolli E, Getz G, Corcoran RB, Juric D. Varkaris A, et al. Among authors: ji y. Cancer Discov. 2024 Feb 8;14(2):227-239. doi: 10.1158/2159-8290.CD-23-0704. Cancer Discov. 2024. PMID: 37916958 Free PMC article.
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.
Varkaris A, Pazolli E, Gunaydin H, Wang Q, Pierce L, Boezio AA, Bulku A, DiPietro L, Fridrich C, Frost A, Giordanetto F, Hamilton EP, Harris K, Holliday M, Hunter TL, Iskandar A, Ji Y, Larivée A, LaRochelle JR, Lescarbeau A, Llambi F, Lormil B, Mader MM, Mar BG, Martin I, McLean TH, Michelsen K, Pechersky Y, Puente-Poushnejad E, Raynor K, Rogala D, Samadani R, Schram AM, Shortsleeves K, Swaminathan S, Tajmir S, Tan G, Tang Y, Valverde R, Wehrenberg B, Wilbur J, Williams BR, Zeng H, Zhang H, Walters WP, Wolf BB, Shaw DE, Bergstrom DA, Watters J, Fraser JS, Fortin PD, Kipp DR. Varkaris A, et al. Among authors: ji y. Cancer Discov. 2024 Feb 8;14(2):240-257. doi: 10.1158/2159-8290.CD-23-0944. Cancer Discov. 2024. PMID: 37916956 Free PMC article.
Adipose-derived stem cells contribute to cardiovascular remodeling.
Ni H, Zhao Y, Ji Y, Shen J, Xiang M, Xie Y. Ni H, et al. Among authors: ji y. Aging (Albany NY). 2019 Dec 4;11(23):11756-11769. doi: 10.18632/aging.102491. Epub 2019 Dec 4. Aging (Albany NY). 2019. PMID: 31800397 Free PMC article. Review.
Cell-modified bioprinted microspheres for vascular regeneration.
Shen J, Ji Y, Xie M, Zhao H, Xuan W, Yin L, Yu X, Xu F, Su S, Nie J, Xie Y, Gao Q, Ma H, Ke X, Shi Z, Fu J, Liu Z, He Y, Xiang M. Shen J, et al. Among authors: ji y. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110896. doi: 10.1016/j.msec.2020.110896. Epub 2020 Mar 23. Mater Sci Eng C Mater Biol Appl. 2020. PMID: 32409053
23 results