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A rational blueprint for the design of chemically-controlled protein switches.
Shui S, Gainza P, Scheller L, Yang C, Kurumida Y, Rosset S, Georgeon S, Di Roberto RB, Castellanos-Rueda R, Reddy ST, Correia BE. Shui S, et al. Among authors: kurumida y. Nat Commun. 2021 Oct 1;12(1):5754. doi: 10.1038/s41467-021-25735-9. Nat Commun. 2021. PMID: 34599176 Free PMC article.
A chemoproteoinformatics approach demonstrates that aspirin increases sensitivity to MEK inhibition by directly binding to RPS5.
Watanabe M, Boku S, Kobayashi K, Kurumida Y, Sukeno M, Masuda M, Mizushima K, Kato C, Iizumi Y, Hirota K, Naito Y, Mutoh M, Kameda T, Sakai T. Watanabe M, et al. Among authors: kurumida y. PNAS Nexus. 2022 May 16;1(2):pgac059. doi: 10.1093/pnasnexus/pgac059. eCollection 2022 May. PNAS Nexus. 2022. PMID: 36713317 Free PMC article.