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Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite-binding site.
Sanders MJ, Ratinaud Y, Neopane K, Bonhoure N, Day EA, Ciclet O, Lassueur S, Naranjo Pinta M, Deak M, Brinon B, Christen S, Steinberg GR, Barron D, Sakamoto K. Sanders MJ, et al. Among authors: ratinaud y. J Biol Chem. 2022 May;298(5):101852. doi: 10.1016/j.jbc.2022.101852. Epub 2022 Mar 21. J Biol Chem. 2022. PMID: 35331736 Free PMC article.
Discovery of a novel series of CXCR3 antagonists.
Crosignani S, Missotten M, Cleva C, Dondi R, Ratinaud Y, Humbert Y, Mandal AB, Bombrun A, Power C, Chollet A, Proudfoot A. Crosignani S, et al. Among authors: ratinaud y. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3614-7. doi: 10.1016/j.bmcl.2010.04.113. Epub 2010 Apr 28. Bioorg Med Chem Lett. 2010. PMID: 20483605
Chemokine receptor antagonist development.
Garin A, Johnson Z, Hermant A, Beltran F, Ratinaud Y, Michel A, Krohn S, Gaudet M, Carboni S, Ji H, Missotten M, Leger O, Power C, Proudfoot A. Garin A, et al. Among authors: ratinaud y. Methods Mol Biol. 2013;1013:67-92. doi: 10.1007/978-1-62703-426-5_6. Methods Mol Biol. 2013. PMID: 23625494