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28 results

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Page 1
Dupilumab in Children with Uncontrolled Moderate-to-Severe Asthma.
Bacharier LB, Maspero JF, Katelaris CH, Fiocchi AG, Gagnon R, de Mir I, Jain N, Sher LD, Mao X, Liu D, Zhang Y, Khan AH, Kapoor U, Khokhar FA, Rowe PJ, Deniz Y, Ruddy M, Laws E, Patel N, Weinreich DM, Yancopoulos GD, Amin N, Mannent LP, Lederer DJ, Hardin M; Liberty Asthma VOYAGE Investigators. Bacharier LB, et al. N Engl J Med. 2021 Dec 9;385(24):2230-2240. doi: 10.1056/NEJMoa2106567. N Engl J Med. 2021. PMID: 34879449 Clinical Trial.
A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice.
Laczkó D, Hogan MJ, Toulmin SA, Hicks P, Lederer K, Gaudette BT, Castaño D, Amanat F, Muramatsu H, Oguin TH 3rd, Ojha A, Zhang L, Mu Z, Parks R, Manzoni TB, Roper B, Strohmeier S, Tombácz I, Arwood L, Nachbagauer R, Karikó K, Greenhouse J, Pessaint L, Porto M, Putman-Taylor T, Strasbaugh A, Campbell TA, Lin PJC, Tam YK, Sempowski GD, Farzan M, Choe H, Saunders KO, Haynes BF, Andersen H, Eisenlohr LC, Weissman D, Krammer F, Bates P, Allman D, Locci M, Pardi N. Laczkó D, et al. Immunity. 2020 Oct 13;53(4):724-732.e7. doi: 10.1016/j.immuni.2020.07.019. Epub 2020 Jul 30. Immunity. 2020. PMID: 32783919 Free PMC article.
An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants.
Liu J, Mao F, Chen J, Lu S, Qi Y, Sun Y, Fang L, Yeung ML, Liu C, Yu G, Li G, Liu X, Yao Y, Huang P, Hao D, Liu Z, Ding Y, Liu H, Yang F, Chen P, Sa R, Sheng Y, Tian X, Peng R, Li X, Luo J, Cheng Y, Zheng Y, Lin Y, Song R, Jin R, Huang B, Choe H, Farzan M, Yuen KY, Tan W, Peng X, Sui J, Li W. Liu J, et al. Nat Commun. 2023 Aug 25;14(1):5191. doi: 10.1038/s41467-023-40933-3. Nat Commun. 2023. PMID: 37626079 Free PMC article.
Genome-wide association study of asthma exacerbations despite inhaled corticosteroid use.
Hernandez-Pacheco N, Vijverberg SJ, Herrera-Luis E, Li J, Sio YY, Granell R, Corrales A, Maroteau C, Lethem R, Perez-Garcia J, Farzan N, Repnik K, Gorenjak M, Soares P, Karimi L, Schieck M, Pérez-Méndez L, Berce V, Tavendale R, Eng C, Sardon O, Kull I, Mukhopadhyay S, Pirmohamed M, Verhamme KMC, Burchard EG, Kabesch M, Hawcutt DB, Melén E, Potočnik U, Chew FT, Tantisira KG, Turner S, Palmer CN, Flores C, Pino-Yanes M, Maitland-van der Zee AH; PiCA and SysPharmPedia consortia. Hernandez-Pacheco N, et al. Eur Respir J. 2021 May 13;57(5):2003388. doi: 10.1183/13993003.03388-2020. Print 2021 May. Eur Respir J. 2021. PMID: 33303529 Free PMC article.
In vivo affinity maturation of murine B cells reprogrammed to express human antibodies.
Yin Y, Guo Y, Jiang Y, Quinlan B, Peng H, Crynen G, He W, Zhang L, Ou T, Bailey CC, Farzan M. Yin Y, et al. bioRxiv [Preprint]. 2023 Oct 23:2023.10.20.563154. doi: 10.1101/2023.10.20.563154. bioRxiv. 2023. PMID: 37961481 Free PMC article. Updated. Preprint.
Cells edited in this way to express the HIV-1 broadly neutralizing antibodies 10-1074 or VRC26.25-y robustly hypermutated and generated potent neutralizing plasma in vaccinated recipient mice. 10-1074 variants isolated from these mice bound and neutralized HIV-1 envelope g …
Cells edited in this way to express the HIV-1 broadly neutralizing antibodies 10-1074 or VRC26.25-y robustly hypermutated and generat …
In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.
Pan A, Bailey CC, Ou T, Xu J, Liu X, Hu B, Crynen G, Skamangas N, Bronkema N, Tran M, Mu H, Zhang X, Yin Y, Alpert MD, He W, Farzan M. Pan A, et al. Res Sq [Preprint]. 2024 Feb 9:rs.3.rs-3922904. doi: 10.21203/rs.3.rs-3922904/v1. Res Sq. 2024. PMID: 38405717 Free PMC article. Preprint.
In vivo affinity maturation of the HIV-1 Env-binding domain of CD4.
Pan A, Bailey CC, Ou T, Xu J, Liu X, Hu B, Crynen G, Skamangas N, Bronkema N, Tran M, Mu H, Zhang X, Yin Y, Alpert MD, He W, Farzan M. Pan A, et al. bioRxiv [Preprint]. 2024 Feb 5:2024.02.03.578630. doi: 10.1101/2024.02.03.578630. bioRxiv. 2024. PMID: 38370774 Free PMC article. Preprint.
Birth outcomes in relation to neighborhood food access and individual food insecurity during pregnancy in the Environmental Influences on Child Health Outcomes (ECHO)-wide cohort study.
Aris IM, Lin PD, Wu AJ, Dabelea D, Lester BM, Wright RJ, Karagas MR, Kerver JM, Dunlop AL, Joseph CL, Camargo CA Jr, Ganiban JM, Schmidt RJ, Strakovsky RS, McEvoy CT, Hipwell AE, O'Shea TM, McCormack LA, Maldonado LE, Niu Z, Ferrara A, Zhu Y, Chehab RF, Kinsey EW, Bush NR, Nguyen RHN, Carroll KN, Barrett ES, Lyall K, Sims-Taylor LM, Trasande L, Biagini JM, Breton CV, Patti MA, Coull B, Amutah-Onukagha N, Hacker MR, James-Todd T, Oken E; program collaborators for Environmental Influences on Child Health Outcomes, ECHO components—Coordinating Center; Data Analysis Center; Person-Reported Outcomes Core; ECHO Awardees and Cohorts. Aris IM, et al. Am J Clin Nutr. 2024 Mar 1:S0002-9165(24)00168-0. doi: 10.1016/j.ajcnut.2024.02.022. Online ahead of print. Am J Clin Nutr. 2024. PMID: 38431121
Mixed-effects models estimated associations with birth outcomes, adjusting for socioeconomic and pregnancy characteristics. RESULTS: Among 22,206 pregnant participants (mean age 30.4 y) with neighborhood food access data, 24.1% resided in LILA neighborhoods and 13.6% in LI …
Mixed-effects models estimated associations with birth outcomes, adjusting for socioeconomic and pregnancy characteristics. RESULTS: Among 2 …
28 results