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Showing results for xue jian han
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The Parkinson's disease-associated mutation LRRK2 G2385R alters mitochondrial biogenesis via the PGC-1α-TFAM pathway.
Xue J, Zhang J, Zhang J, Liu J, Wang F, Li K, Liu C. Xue J, et al. Mitochondrion. 2023 Nov;73:10-18. doi: 10.1016/j.mito.2023.09.002. Epub 2023 Sep 13. Mitochondrion. 2023. PMID: 37708949
Although LRRK2 has been extensively studied, the pathogenic mechanism of the LRRK2 G2385R mutation, which is most common in Asian populations, especially in the Chinese Han population, remains unclear. In this study, we demonstrated that the LRRK2 G2385R mutation in HEK293 …
Although LRRK2 has been extensively studied, the pathogenic mechanism of the LRRK2 G2385R mutation, which is most common in Asian population …
Integrated massively parallel sequencing of 15 autosomal STRs and Amelogenin using a simplified library preparation approach.
Xue J, Wu R, Pan Y, Wang S, Qu B, Qin Y, Shi Y, Zhang C, Li R, Zhang L, Zhou C, Sun H. Xue J, et al. Electrophoresis. 2018 Jun;39(12):1466-1473. doi: 10.1002/elps.201700429. Epub 2018 Apr 25. Electrophoresis. 2018. PMID: 29608791
In this study, a 16-plex STR typing system was designed with fusion primer strategy based on the Ion Torrent S5 XL platform which could effectively resolve the above challenges for forensic DNA database-type samples (bloodstains, saliva stains, etc.). The efficiency of this syste …
In this study, a 16-plex STR typing system was designed with fusion primer strategy based on the Ion Torrent S5 XL platform which could effe …
Interferon-Inducible Transmembrane Protein 3 Genetic Variant rs12252 and Influenza Susceptibility and Severity: A Meta-Analysis.
Yang X, Tan B, Zhou X, Xue J, Zhang X, Wang P, Shao C, Li Y, Li C, Xia H, Qiu J. Yang X, et al. Among authors: xue j. PLoS One. 2015 May 5;10(5):e0124985. doi: 10.1371/journal.pone.0124985. eCollection 2015. PLoS One. 2015. PMID: 25942469 Free PMC article.
CONCLUSION: Our meta-analysis suggests a significant association between a minor IFITM3 allele (SNP rs12252-C) with severe influenza susceptibility, but not in mild influenza subjects, in both UK Caucasians and Han Chinese population. The rs12252-C allele causes a 23.7% hi …
CONCLUSION: Our meta-analysis suggests a significant association between a minor IFITM3 allele (SNP rs12252-C) with severe influenza suscept …