Effects of preventive care on psychological state and complications in leukemia patients receiving chemotherapy

Objective: To investigate the effects of preventive care on the psychological state and complications in patients with leukemia undergoing chemotherapy.

Methods: Retrospectively, 85 patients with leukemia undergoing chemotherapy in Xinchang People's Hospital from April 2019 to September 2021 were collected, including 47 patients who received preventive care as an observation group and 38 patients who received routine care as a control group. The incidence of chemotherapy-related complications, the scores of Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) before and after nursing intervention, and the General Comfort Questionnaire (GCQ) and nursing satisfaction were compared between the two groups.

Results: The complication rate in the control group was higher than that of the observation group (P<0.05). The SAS and SDS scores of the control group were higher than those of the observation group after care (P<0.05). The GCQ score of the observation group was higher than that of the control group after care (P<0.05), and the care satisfaction of the control group was lower than that of the observation group (P<0.05). Multivariate Logistic regression analysis showed that age over 65 years old, platelet count less than 50 × 10⁹/L and white blood cell count over 100 × 10⁹/L were risk factors for complications in leukemia patients receiving chemotherapy (P<0.05).

Conclusion: Preventive care helps to improve the negative emotions of patients with leukemia undergoing chemotherapy and reduces complications.