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Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance.
Garcia LR, Tenev T, Newman R, Haich RO, Liccardi G, John SW, Annibaldi A, Yu L, Pardo M, Young SN, Fitzgibbon C, Fernando W, Guppy N, Kim H, Liang LY, Lucet IS, Kueh A, Roxanis I, Gazinska P, Sims M, Smyth T, Ward G, Bertin J, Beal AM, Geddes B, Choudhary JS, Murphy JM, Aurelia Ball K, Upton JW, Meier P. Garcia LR, et al. Among authors: fernando w. Nat Commun. 2021 Jun 7;12(1):3364. doi: 10.1038/s41467-021-23474-5. Nat Commun. 2021. PMID: 34099649 Free PMC article.
CEP55 is a determinant of cell fate during perturbed mitosis in breast cancer.
Kalimutho M, Sinha D, Jeffery J, Nones K, Srihari S, Fernando WC, Duijf PH, Vennin C, Raninga P, Nanayakkara D, Mittal D, Saunus JM, Lakhani SR, López JA, Spring KJ, Timpson P, Gabrielli B, Waddell N, Khanna KK. Kalimutho M, et al. Among authors: fernando wc. EMBO Mol Med. 2018 Sep;10(9):e8566. doi: 10.15252/emmm.201708566. EMBO Mol Med. 2018. PMID: 30108112 Free PMC article.
APC Mutation Marks an Aggressive Subtype of BRAF Mutant Colorectal Cancers.
Fennell LJ, Kane A, Liu C, McKeone D, Fernando W, Su C, Bond C, Jamieson S, Dumenil T, Patch AM, Kazakoff SH, Pearson JV, Waddell N, Leggett B, Whitehall VLJ. Fennell LJ, et al. Among authors: fernando w. Cancers (Basel). 2020 May 6;12(5):1171. doi: 10.3390/cancers12051171. Cancers (Basel). 2020. PMID: 32384699 Free PMC article.
Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia.
Bond CE, Liu C, Kawamata F, McKeone DM, Fernando W, Jamieson S, Pearson SA, Kane A, Woods SL, Lannagan TRM, Somashekar R, Lee Y, Dumenil T, Hartel G, Spring KJ, Borowsky J, Fennell L, Bettington M, Lee J, Worthley DL, Leggett BA, Whitehall VLJ. Bond CE, et al. Among authors: fernando w. Epigenetics. 2018;13(1):40-48. doi: 10.1080/15592294.2017.1411446. Epub 2018 Feb 19. Epigenetics. 2018. PMID: 29235923 Free PMC article.
Multiple interaction nodes define the postreplication repair response to UV-induced DNA damage that is defective in melanomas and correlated with UV signature mutation load.
Pavey S, Pinder A, Fernando W, D'Arcy N, Matigian N, Skalamera D, Lê Cao KA, Loo-Oey D, Hill MM, Stark M, Kimlin M, Burgess A, Cloonan N, Sturm RA, Gabrielli B. Pavey S, et al. Among authors: fernando w. Mol Oncol. 2020 Jan;14(1):22-41. doi: 10.1002/1878-0261.12601. Epub 2019 Dec 19. Mol Oncol. 2020. PMID: 31733171 Free PMC article.