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Page 1
Interrogating the hidden phosphoproteome.
Kang UB, Alexander WM, Marto JA. Kang UB, et al. Among authors: alexander wm. Proteomics. 2017 Mar;17(6):10.1002/pmic.201600437. doi: 10.1002/pmic.201600437. Proteomics. 2017. PMID: 28165663 Free PMC article.
Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis.
Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA. Chu N, et al. Among authors: alexander wm. Cell. 2018 Aug 9;174(4):897-907.e14. doi: 10.1016/j.cell.2018.07.003. Epub 2018 Aug 2. Cell. 2018. PMID: 30078705 Free PMC article.
PRM-LIVE with Trapped Ion Mobility Spectrometry and Its Application in Selectivity Profiling of Kinase Inhibitors.
Zhu H, Ficarro SB, Alexander WM, Fleming LE, Adelmant G, Zhang T, Willetts M, Decker J, Brehmer S, Krause M, East MP, Gray NS, Johnson GL, Kruppa G, Marto JA. Zhu H, et al. Among authors: alexander wm. Anal Chem. 2021 Oct 19;93(41):13791-13799. doi: 10.1021/acs.analchem.1c02349. Epub 2021 Oct 4. Anal Chem. 2021. PMID: 34606255 Free PMC article.
A Chemoproteomic Strategy for Direct and Proteome-Wide Covalent Inhibitor Target-Site Identification.
Browne CM, Jiang B, Ficarro SB, Doctor ZM, Johnson JL, Card JD, Sivakumaren SC, Alexander WM, Yaron TM, Murphy CJ, Kwiatkowski NP, Zhang T, Cantley LC, Gray NS, Marto JA. Browne CM, et al. Among authors: alexander wm. J Am Chem Soc. 2019 Jan 9;141(1):191-203. doi: 10.1021/jacs.8b07911. Epub 2018 Dec 20. J Am Chem Soc. 2019. PMID: 30518210 Free PMC article.
Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes.
Ficarro SB, Browne CM, Card JD, Alexander WM, Zhang T, Park E, McNally R, Dhe-Paganon S, Seo HS, Lamberto I, Eck MJ, Buhrlage SJ, Gray NS, Marto JA. Ficarro SB, et al. Among authors: alexander wm. Anal Chem. 2016 Dec 20;88(24):12248-12254. doi: 10.1021/acs.analchem.6b03394. Epub 2016 Nov 30. Anal Chem. 2016. PMID: 28193034