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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 2
2006 1
2007 1
2008 1
2009 5
2010 3
2011 5
2012 5
2013 2
2014 5
2015 9
2016 7
2017 3
2018 3
2019 6
2020 4
2021 1
2022 2
2023 2
2024 0

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60 results

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Page 1
Covalent-Allosteric Kinase Inhibitors.
Weisner J, Gontla R, van der Westhuizen L, Oeck S, Ketzer J, Janning P, Richters A, Mühlenberg T, Fang Z, Taher A, Jendrossek V, Pelly SC, Bauer S, van Otterlo WA, Rauh D. Weisner J, et al. Among authors: van otterlo wa. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10313-6. doi: 10.1002/anie.201502142. Epub 2015 Jun 25. Angew Chem Int Ed Engl. 2015. PMID: 26110718
Toward a Cancer Drug of Fungal Origin.
Kornienko A, Evidente A, Vurro M, Mathieu V, Cimmino A, Evidente M, van Otterlo WA, Dasari R, Lefranc F, Kiss R. Kornienko A, et al. Among authors: van otterlo wa. Med Res Rev. 2015 Sep;35(5):937-67. doi: 10.1002/med.21348. Epub 2015 Apr 8. Med Res Rev. 2015. PMID: 25850821 Free PMC article. Review.
The Phylum Bryozoa: From Biology to Biomedical Potential.
Ciavatta ML, Lefranc F, Vieira LM, Kiss R, Carbone M, van Otterlo WAL, Lopanik NB, Waeschenbach A. Ciavatta ML, et al. Among authors: van otterlo wal. Mar Drugs. 2020 Apr 9;18(4):200. doi: 10.3390/md18040200. Mar Drugs. 2020. PMID: 32283669 Free PMC article. Review.
Isomerization of allylbenzenes.
Hassam M, Taher A, Arnott GE, Green IR, van Otterlo WA. Hassam M, et al. Among authors: van otterlo wa. Chem Rev. 2015 Jun 10;115(11):5462-569. doi: 10.1021/acs.chemrev.5b00052. Epub 2015 May 20. Chem Rev. 2015. PMID: 25993416 No abstract available.
Covalent Allosteric Inhibitors of Akt Generated Using a Click Fragment Approach.
van der Westhuizen L, Weisner J, Taher A, Landel I, Quambusch L, Lindemann M, Uhlenbrock N, Müller MP, Green IR, Pelly SC, Rauh D, van Otterlo WAL. van der Westhuizen L, et al. Among authors: van otterlo wal. ChemMedChem. 2022 May 18;17(10):e202100776. doi: 10.1002/cmdc.202100776. Epub 2022 Mar 9. ChemMedChem. 2022. PMID: 35170857 Free PMC article.
Metathesis in the synthesis of aromatic compounds.
van Otterlo WA, de Koning CB. van Otterlo WA, et al. Chem Rev. 2009 Aug;109(8):3743-82. doi: 10.1021/cr900178p. Chem Rev. 2009. PMID: 19618929 Review. No abstract available.
Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
Lategahn J, Hardick J, Grabe T, Niggenaber J, Jeyakumar K, Keul M, Tumbrink HL, Becker C, Hodson L, Kirschner T, Klövekorn P, Ketzer J, Baumann M, Terheyden S, Unger A, Weisner J, Müller MP, van Otterlo WAL, Bauer S, Rauh D. Lategahn J, et al. Among authors: van otterlo wal. J Med Chem. 2020 Oct 22;63(20):11725-11755. doi: 10.1021/acs.jmedchem.0c00870. Epub 2020 Sep 30. J Med Chem. 2020. PMID: 32931277
A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice.
Sabarwal A, van Rooyen JC, Caburet J, Avgenikos M, Dheeraj A, Ali M, Mishra D, de Meester JSB, Stander S, van Otterlo WAL, Kaschula CH, Singh RP. Sabarwal A, et al. Among authors: van otterlo wal. FASEB J. 2022 Dec;36(12):e22654. doi: 10.1096/fj.202200669RR. FASEB J. 2022. PMID: 36421014
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.
Lategahn J, Keul M, Klövekorn P, Tumbrink HL, Niggenaber J, Müller MP, Hodson L, Flaßhoff M, Hardick J, Grabe T, Engel J, Schultz-Fademrecht C, Baumann M, Ketzer J, Mühlenberg T, Hiller W, Günther G, Unger A, Müller H, Heimsoeth A, Golz C, Blank-Landeshammer B, Kollipara L, Zahedi RP, Strohmann C, Hengstler JG, van Otterlo WAL, Bauer S, Rauh D. Lategahn J, et al. Among authors: van otterlo wal. Chem Sci. 2019 Oct 4;10(46):10789-10801. doi: 10.1039/c9sc03445e. eCollection 2019 Dec 14. Chem Sci. 2019. PMID: 31857889 Free PMC article.
60 results