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Page 1
Broad anti-pathogen potential of DEAD box RNA helicase eIF4A-targeting rocaglates.
Obermann W, Azri MFD, Konopka L, Schmidt N, Magari F, Sherman J, Silva LMR, Hermosilla C, Ludewig AH, Houhou H, Haeberlein S, Luo MY, Häcker I, Schetelig MF, Grevelding CG, Schroeder FC, Lau GSK, Taubert A, Rodriguez A, Heine A, Yeo TC, Grünweller A, Taroncher-Oldenburg G. Obermann W, et al. Sci Rep. 2023 Jun 8;13(1):9297. doi: 10.1038/s41598-023-35765-6. Sci Rep. 2023. PMID: 37291191 Free PMC article.
Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers.
Peiffer KH, Spengler C, Basic M, Jiang B, Kuhnhenn L, Obermann W, Zahn T, Glitscher M, Loglio A, Facchetti F, Carra G, Kubesch A, Vermehren J, Knop V, Graf C, Dietz J, Finkelmeier F, Herrmann E, Trebicka J, Grünweller A, Zeuzem S, Sarrazin C, Lampertico P, Hildt E. Peiffer KH, et al. Among authors: obermann w. JCI Insight. 2020 Nov 19;5(22):e135833. doi: 10.1172/jci.insight.135833. JCI Insight. 2020. PMID: 33055418 Free PMC article.
Comparison of broad-spectrum antiviral activities of the synthetic rocaglate CR-31-B (-) and the eIF4A-inhibitor Silvestrol.
Müller C, Obermann W, Schulte FW, Lange-Grünweller K, Oestereich L, Elgner F, Glitscher M, Hildt E, Singh K, Wendel HG, Hartmann RK, Ziebuhr J, Grünweller A. Müller C, et al. Among authors: obermann w. Antiviral Res. 2020 Mar;175:104706. doi: 10.1016/j.antiviral.2020.104706. Epub 2020 Jan 10. Antiviral Res. 2020. PMID: 31931103 Free PMC article.