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Page 1
Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection.
Hollenhorst MI, Nandigama R, Evers SB, Gamayun I, Abdel Wadood N, Salah A, Pieper M, Wyatt A, Stukalov A, Gebhardt A, Nadolni W, Burow W, Herr C, Beisswenger C, Kusumakshi S, Ectors F, Kichko TI, Hübner L, Reeh P, Munder A, Wienhold SM, Witzenrath M, Bals R, Flockerzi V, Gudermann T, Bischoff M, Lipp P, Zierler S, Chubanov V, Pichlmair A, König P, Boehm U, Krasteva-Christ G. Hollenhorst MI, et al. Among authors: nadolni w. J Clin Invest. 2022 Jul 1;132(13):e150951. doi: 10.1172/JCI150951. J Clin Invest. 2022. PMID: 35503420 Free PMC article.
Inactivation of TRPM7 Kinase Targets AKT Signaling and Cyclooxygenase-2 Expression in Human CML Cells.
Hoeger B, Nadolni W, Hampe S, Hoelting K, Fraticelli M, Zaborsky N, Madlmayr A, Sperrer V, Fraticelli L, Addington L, Steinritz D, Chubanov V, Geisberger R, Greil R, Breit A, Boekhoff I, Gudermann T, Zierler S. Hoeger B, et al. Among authors: nadolni w. Function (Oxf). 2023 Sep 15;4(6):zqad053. doi: 10.1093/function/zqad053. eCollection 2023. Function (Oxf). 2023. PMID: 37786778 Free PMC article.
The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation.
Immler R, Nadolni W, Bertsch A, Morikis V, Rohwedder I, Masgrau-Alsina S, Schroll T, Yevtushenko A, Soehnlein O, Moser M, Gudermann T, Barnea ER, Rehberg M, Simon SI, Zierler S, Pruenster M, Sperandio M. Immler R, et al. Among authors: nadolni w. Cardiovasc Res. 2022 Mar 25;118(5):1289-1302. doi: 10.1093/cvr/cvab133. Cardiovasc Res. 2022. PMID: 33881519 Free PMC article.
Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.
Voringer S, Schreyer L, Nadolni W, Meier MA, Woerther K, Mittermeier C, Ferioli S, Singer S, Holzer K, Zierler S, Chubanov V, Liebl B, Gudermann T, Muehlich S. Voringer S, et al. Among authors: nadolni w. Oncogene. 2020 Mar;39(11):2328-2344. doi: 10.1038/s41388-019-1140-8. Epub 2019 Dec 16. Oncogene. 2020. PMID: 31844251
TPC1 deficiency or blockade augments systemic anaphylaxis and mast cell activity.
Arlt E, Fraticelli M, Tsvilovskyy V, Nadolni W, Breit A, O'Neill TJ, Resenberger S, Wennemuth G, Wahl-Schott C, Biel M, Grimm C, Freichel M, Gudermann T, Klugbauer N, Boekhoff I, Zierler S. Arlt E, et al. Among authors: nadolni w. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18068-18078. doi: 10.1073/pnas.1920122117. Epub 2020 Jul 13. Proc Natl Acad Sci U S A. 2020. PMID: 32661165 Free PMC article.
TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut.
Romagnani A, Vettore V, Rezzonico-Jost T, Hampe S, Rottoli E, Nadolni W, Perotti M, Meier MA, Hermanns C, Geiger S, Wennemuth G, Recordati C, Matsushita M, Muehlich S, Proietti M, Chubanov V, Gudermann T, Grassi F, Zierler S. Romagnani A, et al. Among authors: nadolni w. Nat Commun. 2017 Dec 4;8(1):1917. doi: 10.1038/s41467-017-01960-z. Nat Commun. 2017. PMID: 29203869 Free PMC article.