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Detrimental proarrhythmogenic interaction of Ca2+/calmodulin-dependent protein kinase II and NaV1.8 in heart failure.
Bengel P, Dybkova N, Tirilomis P, Ahmad S, Hartmann N, A Mohamed B, Krekeler MC, Maurer W, Pabel S, Trum M, Mustroph J, Gummert J, Milting H, Wagner S, Ljubojevic-Holzer S, Toischer K, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S. Bengel P, et al. Among authors: maurer w. Nat Commun. 2021 Nov 15;12(1):6586. doi: 10.1038/s41467-021-26690-1. Nat Commun. 2021. PMID: 34782600 Free PMC article.
Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients.
Haupt LP, Rebs S, Maurer W, Hübscher D, Tiburcy M, Pabel S, Maus A, Köhne S, Tappu R, Haas J, Li Y, Sasse A, Santos CCX, Dressel R, Wojnowski L, Bunt G, Möbius W, Shah AM, Meder B, Wollnik B, Sossalla S, Hasenfuss G, Streckfuss-Bömeke K. Haupt LP, et al. Among authors: maurer w. Basic Res Cardiol. 2022 Mar 8;117(1):13. doi: 10.1007/s00395-022-00918-7. Basic Res Cardiol. 2022. PMID: 35260914 Free PMC article.
Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation.
Maurer W, Rebs S, Köhne S, Eberl H, Wollnik B, Zibat A, Streckfuss-Bömeke K. Maurer W, et al. Stem Cell Res. 2024 Mar 29;77:103409. doi: 10.1016/j.scr.2024.103409. Online ahead of print. Stem Cell Res. 2024. PMID: 38583294 Free article.