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2018 2
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2023 4
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Page 1
Structural basis for inactivation of PRC2 by G-quadruplex RNA.
Song J, Gooding AR, Hemphill WO, Love BD, Robertson A, Yao L, Zon LI, North TE, Kasinath V, Cech TR. Song J, et al. Among authors: hemphill wo. Science. 2023 Sep 22;381(6664):1331-1337. doi: 10.1126/science.adh0059. Epub 2023 Sep 21. Science. 2023. PMID: 37733873
TREX1 as a Novel Immunotherapeutic Target.
Hemphill WO, Simpson SR, Liu M, Salsbury FR Jr, Hollis T, Grayson JM, Perrino FW. Hemphill WO, et al. Front Immunol. 2021 Apr 1;12:660184. doi: 10.3389/fimmu.2021.660184. eCollection 2021. Front Immunol. 2021. PMID: 33868310 Free PMC article.
Structural basis for inactivation of PRC2 by G-quadruplex RNA.
Song J, Gooding AR, Hemphill WO, Kasinath V, Cech TR. Song J, et al. Among authors: hemphill wo. bioRxiv [Preprint]. 2023 Feb 6:2023.02.06.527314. doi: 10.1101/2023.02.06.527314. bioRxiv. 2023. PMID: 36798278 Free PMC article. Updated. Preprint.
Measuring TREX1 and TREX2 exonuclease activities.
Hemphill WO, Perrino FW. Hemphill WO, et al. Methods Enzymol. 2019;625:109-133. doi: 10.1016/bs.mie.2019.05.004. Epub 2019 Jun 8. Methods Enzymol. 2019. PMID: 31455522 Free PMC article.
TREX1 - Apex predator of cytosolic DNA metabolism.
Simpson SR, Hemphill WO, Hudson T, Perrino FW. Simpson SR, et al. Among authors: hemphill wo. DNA Repair (Amst). 2020 Oct;94:102894. doi: 10.1016/j.dnarep.2020.102894. Epub 2020 Jun 12. DNA Repair (Amst). 2020. PMID: 32615442 Free PMC article.
Genotype-Phenotype Correlation and Functional Insights for Two Monoallelic TREX1 Missense Variants Affecting the Catalytic Core.
Amico G, Hemphill WO, Severino M, Moratti C, Pascarella R, Bertamino M, Napoli F, Volpi S, Rosamilia F, Signa S, Perrino F, Zedde M, Ceccherini I, On Behalf Of The Gaslini Stroke Study Group. Amico G, et al. Among authors: hemphill wo. Genes (Basel). 2022 Jun 30;13(7):1179. doi: 10.3390/genes13071179. Genes (Basel). 2022. PMID: 35885962 Free PMC article.
T Cells Produce IFN-α in the TREX1 D18N Model of Lupus-like Autoimmunity.
Simpson SR, Rego SL, Harvey SE, Liu M, Hemphill WO, Venkatadri R, Sharma R, Grayson JM, Perrino FW. Simpson SR, et al. Among authors: hemphill wo. J Immunol. 2020 Jan 15;204(2):348-359. doi: 10.4049/jimmunol.1900220. Epub 2019 Dec 11. J Immunol. 2020. PMID: 31826941 Free PMC article.
12 results