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Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes.
Júnior WB, Alexandre-Moreira MS, Alves MA, Perez-Rebolledo A, Parrilha GL, Castellano EE, Piro OE, Barreiro EJ, Lima LM, Beraldo H. Júnior WB, et al. Molecules. 2011 Aug 15;16(8):6902-15. doi: 10.3390/molecules16086902. Molecules. 2011. PMID: 21844840 Free PMC article.
Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates.
da Silva YK, Augusto CV, de Castro Barbosa ML, de Albuquerque Melo GM, de Queiroz AC, de Lima Matos Freire Dias T, Júnior WB, Barreiro EJ, Lima LM, Alexandre-Moreira MS. da Silva YK, et al. Among authors: junior wb. Bioorg Med Chem. 2010 Jul 15;18(14):5007-15. doi: 10.1016/j.bmc.2010.06.002. Epub 2010 Jun 8. Bioorg Med Chem. 2010. PMID: 20598893