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Preclinical safety and efficacy of a therapeutic antibody that targets SARS-CoV-2 at the sotrovimab face but is escaped by Omicron.
Kreye J, Reincke SM, Edelburg S, Jeworowski LM, Kornau HC, Trimpert J, Hombach P, Halbe S, Nölle V, Meyer M, Kattenbach S, Sánchez-Sendin E, Schmidt ML, Schwarz T, Rose R, Krumbholz A, Merz S, Adler JM, Eschke K, Abdelgawad A, Schmitz D, Sander LE, Janssen U, Corman VM, Prüss H. Kreye J, et al. Among authors: nolle v. iScience. 2023 Apr 21;26(4):106323. doi: 10.1016/j.isci.2023.106323. Epub 2023 Mar 2. iScience. 2023. PMID: 36925720 Free PMC article.
Design of a novel switchable antibody display system in Pichia pastoris.
Gätjen D, Tomszak F, Dettmann JC, Droste M, Nölle V, Wieczorek M. Gätjen D, et al. Among authors: nolle v. Appl Microbiol Biotechnol. 2022 Sep;106(18):6209-6224. doi: 10.1007/s00253-022-12108-5. Epub 2022 Aug 12. Appl Microbiol Biotechnol. 2022. PMID: 35953606