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Synthesis and evaluation of a new class of MIF-inhibitors in activated macrophage cells and in experimental septic shock in mice.
Garai J, Radnai B, Vámos E, Kovács D, Vántus VB, Rumbus Z, Pákai E, Garami A, Gulyás-Fekete G, Agócs A, Krekó M, Zaman K, Prókai L, Őrfi L, Jakus PB, Lóránd T. Garai J, et al. Among authors: vantus vb. Eur J Med Chem. 2023 Feb 5;247:115050. doi: 10.1016/j.ejmech.2022.115050. Epub 2022 Dec 28. Eur J Med Chem. 2023. PMID: 36587420 Free article.
Tetralone derivatives are MIF tautomerase inhibitors and attenuate macrophage activation and amplify the hypothermic response in endotoxemic mice.
Garai J, Krekó M, Őrfi L, Jakus PB, Rumbus Z, Kéringer P, Garami A, Vámos E, Kovács D, Bagóné Vántus V, Radnai B, Lóránd T. Garai J, et al. Among authors: bagone vantus v. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1357-1369. doi: 10.1080/14756366.2021.1916010. J Enzyme Inhib Med Chem. 2021. PMID: 34225560 Free PMC article.
Olaparib: A Clinically Applied PARP Inhibitor Protects from Experimental Crohn's Disease and Maintains Barrier Integrity by Improving Bioenergetics through Rescuing Glycolysis in Colonic Epithelial Cells.
Kovács D, Vántus VB, Vámos E, Kálmán N, Schicho R, Gallyas F, Radnai B. Kovács D, et al. Among authors: vantus vb. Oxid Med Cell Longev. 2021 Sep 14;2021:7308897. doi: 10.1155/2021/7308897. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34567413 Free PMC article.