Rare refractory Kawasaki disease in an adolescent boy with cardiac and diffuse coronary artery involvement

Rima Šileikienė; Jolanta Kudzytė; Antanas Jankauskas; Liutauras Labanauskas; Vilma Rakauskienė; Nemira Jurkienė; Rimantas Kėvalas

Rare refractory Kawasaki disease in an adolescent boy with cardiac and diffuse coronary artery involvement

Medicina (Kaunas). 2013;49(7):341-5.

Authors

Rima Šileikienė¹, Jolanta Kudzytė, Antanas Jankauskas, Liutauras Labanauskas, Vilma Rakauskienė, Nemira Jurkienė, Rimantas Kėvalas

Affiliation

¹ Department of Children Diseases, Medical Academy, Lithuanian University of Health Scien-ces, Eivenių 2, 50161 Kaunas, Lithuania. rima.sileikiene@kaunoklinikos.lt.

PMID: 24375247

Abstract

Kawasaki disease is an acute multisystemic vasculitis occurring predominantly in infants and young children and rarely in adolescents and adults. At elderly age, Kawasaki disease may remain unrecognized with a subsequent delay in appropriate therapy and an increased risk of coronary artery aneurysms. We report a case of intravenous immunoglobulin- and aspirin-resistant Kawasaki disease and severe cardiovascular damage in an adolescent boy. The article discusses major issues associated with the management of refractory Kawasaki disease.

Publication types

Case Reports

MeSH terms

Adolescent
Anticoagulants / therapeutic use
Aspirin / therapeutic use
Coronary Aneurysm / diagnosis*
Coronary Aneurysm / etiology
Drug Resistance
Humans
Immunoglobulins, Intravenous / therapeutic use
Male
Mucocutaneous Lymph Node Syndrome / complications
Mucocutaneous Lymph Node Syndrome / diagnosis*
Mucocutaneous Lymph Node Syndrome / drug therapy
Rare Diseases / complications
Rare Diseases / diagnosis*
Rare Diseases / drug therapy
Treatment Outcome
Warfarin / therapeutic use

Substances

Anticoagulants
Immunoglobulins, Intravenous
Warfarin
Aspirin