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MiR-129-5p exerts Wnt signaling-dependent tumor-suppressive functions in hepatocellular carcinoma by directly targeting hepatoma-derived growth factor HDGF.
Huge N, Reinkens T, Buurman R, Sandbothe M, Bergmann A, Wallaschek H, Vajen B, Stalke A, Decker M, Eilers M, Schäffer V, Dittrich-Breiholz O, Gürlevik E, Kühnel F, Schlegelberger B, Illig T, Skawran B. Huge N, et al. Among authors: schaffer v. Cancer Cell Int. 2022 May 16;22(1):192. doi: 10.1186/s12935-022-02582-2. Cancer Cell Int. 2022. PMID: 35578240 Free PMC article.
Wnt status-dependent oncogenic role of BCL9 and BCL9L in hepatocellular carcinoma.
Huge N, Sandbothe M, Schröder AK, Stalke A, Eilers M, Schäffer V, Schlegelberger B, Illig T, Vajen B, Skawran B. Huge N, et al. Among authors: schaffer v. Hepatol Int. 2020 May;14(3):373-384. doi: 10.1007/s12072-019-09977-w. Epub 2019 Aug 22. Hepatol Int. 2020. PMID: 31440992 Free PMC article.
The microRNA-449 family inhibits TGF-β-mediated liver cancer cell migration by targeting SOX4.
Sandbothe M, Buurman R, Reich N, Greiwe L, Vajen B, Gürlevik E, Schäffer V, Eilers M, Kühnel F, Vaquero A, Longerich T, Roessler S, Schirmacher P, Manns MP, Illig T, Schlegelberger B, Skawran B. Sandbothe M, et al. Among authors: schaffer v. J Hepatol. 2017 May;66(5):1012-1021. doi: 10.1016/j.jhep.2017.01.004. Epub 2017 Jan 11. J Hepatol. 2017. PMID: 28088579
Homozygous frame shift variant in ATP7B exon 1 leads to bypass of nonsense-mediated mRNA decay and to a protein capable of copper export.
Stalke A, Pfister ED, Baumann U, Eilers M, Schäffer V, Illig T, Auber B, Schlegelberger B, Brackmann R, Prokisch H, Krooss S, Bohne J, Skawran B. Stalke A, et al. Among authors: schaffer v. Eur J Hum Genet. 2019 Jun;27(6):879-887. doi: 10.1038/s41431-019-0345-1. Epub 2019 Feb 5. Eur J Hum Genet. 2019. PMID: 30723317 Free PMC article.