Varnavas D. Mouchlis - Search Results

Year	Number of Results
2010	3
2011	1
2012	2
2013	2
2015	2
2016	5
2017	3
2018	4
2019	4
2020	3
2021	3
2022	4
2024	1

1

Phospholipase A₂ catalysis and lipid mediator lipidomics.

Mouchlis VD, Dennis EA. Mouchlis VD, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun;1864(6):766-771. doi: 10.1016/j.bbalip.2018.08.010. Epub 2018 Aug 23. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30905345 Free PMC article. Review.

2

Review of four major distinct types of human phospholipase A₂.

Vasquez AM, Mouchlis VD, Dennis EA. Vasquez AM, et al. Among authors: mouchlis vd. Adv Biol Regul. 2018 Jan;67:212-218. doi: 10.1016/j.jbior.2017.10.009. Epub 2017 Oct 23. Adv Biol Regul. 2018. PMID: 29248300 Free PMC article. Review.

3

Membrane and inhibitor interactions of intracellular phospholipases A2.

Mouchlis VD, Dennis EA. Mouchlis VD, et al. Adv Biol Regul. 2016 May;61:17-24. doi: 10.1016/j.jbior.2015.11.011. Epub 2015 Dec 19. Adv Biol Regul. 2016. PMID: 26774606 Free PMC article. Review.

4

Advances in de Novo Drug Design: From Conventional to Machine Learning Methods.

Mouchlis VD, Afantitis A, Serra A, Fratello M, Papadiamantis AG, Aidinis V, Lynch I, Greco D, Melagraki G. Mouchlis VD, et al. Int J Mol Sci. 2021 Feb 7;22(4):1676. doi: 10.3390/ijms22041676. Int J Mol Sci. 2021. PMID: 33562347 Free PMC article. Review.

5

Computer-Aided Drug Design of β-Secretase, γ-Secretase and Anti-Tau Inhibitors for the Discovery of Novel Alzheimer's Therapeutics.

Mouchlis VD, Melagraki G, Zacharia LC, Afantitis A. Mouchlis VD, et al. Int J Mol Sci. 2020 Jan 21;21(3):703. doi: 10.3390/ijms21030703. Int J Mol Sci. 2020. PMID: 31973122 Free PMC article. Review.

6

2-Oxoester Phospholipase A₂ Inhibitors with Enhanced Metabolic Stability.

Koutoulogenis GS, Kokotou MG, Hayashi D, Mouchlis VD, Dennis EA, Kokotos G. Koutoulogenis GS, et al. Among authors: mouchlis vd. Biomolecules. 2020 Mar 24;10(3):491. doi: 10.3390/biom10030491. Biomolecules. 2020. PMID: 32213911 Free PMC article.

7

Lipoprotein-associated phospholipase A₂: A paradigm for allosteric regulation by membranes.

Mouchlis VD, Hayashi D, Vasquez AM, Cao J, McCammon JA, Dennis EA. Mouchlis VD, et al. Proc Natl Acad Sci U S A. 2022 Jan 11;119(2):e2102953118. doi: 10.1073/pnas.2102953118. Proc Natl Acad Sci U S A. 2022. PMID: 34996868 Free PMC article.

8

Each phospholipase A₂ type exhibits distinct selectivity toward sn-1 ester, alkyl ether, and vinyl ether phospholipids.

Hayashi D, Mouchlis VD, Dennis EA. Hayashi D, et al. Among authors: mouchlis vd. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jan;1867(1):159067. doi: 10.1016/j.bbalip.2021.159067. Epub 2021 Oct 9. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 34634490 Free PMC article.

9

Membrane Association Allosterically Regulates Phospholipase A₂ Enzymes and Their Specificity.

Mouchlis VD, Dennis EA. Mouchlis VD, et al. Acc Chem Res. 2022 Dec 6;55(23):3303-3311. doi: 10.1021/acs.accounts.2c00497. Epub 2022 Oct 31. Acc Chem Res. 2022. PMID: 36315840 Free PMC article.

10

Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A₂ inhibitors.

Mouchlis VD, Mu C, Hammons R, Dennis EA. Mouchlis VD, et al. Adv Biol Regul. 2020 May;76:100719. doi: 10.1016/j.jbior.2020.100719. Epub 2020 Mar 10. Adv Biol Regul. 2020. PMID: 32199750 Free PMC article.

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