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Dual-mechanism estrogen receptor inhibitors.
Min J, Nwachukwu JC, Min CK, Njeri JW, Srinivasan S, Rangarajan ES, Nettles CC, Sanabria Guillen V, Ziegler Y, Yan S, Carlson KE, Hou Y, Kim SH, Novick S, Pascal BD, Houtman R, Griffin PR, Izard T, Katzenellenbogen BS, Katzenellenbogen JA, Nettles KW. Min J, et al. Among authors: sanabria guillen v. Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):e2101657118. doi: 10.1073/pnas.2101657118. Proc Natl Acad Sci U S A. 2021. PMID: 34452998 Free PMC article.
Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain.
Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Sharma A, et al. Among authors: guillen vs. ACS Chem Biol. 2018 Dec 21;13(12):3374-3384. doi: 10.1021/acschembio.8b00877. Epub 2018 Nov 26. ACS Chem Biol. 2018. PMID: 30404440 Free PMC article.
Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds.
Ziegler Y, Laws MJ, Sanabria Guillen V, Kim SH, Dey P, Smith BP, Gong P, Bindman N, Zhao Y, Carlson K, Yasuda MA, Singh D, Li Z, El-Ashry D, Madak-Erdogan Z, Katzenellenbogen JA, Katzenellenbogen BS. Ziegler Y, et al. Among authors: sanabria guillen v. NPJ Breast Cancer. 2019 Nov 29;5:45. doi: 10.1038/s41523-019-0141-7. eCollection 2019. NPJ Breast Cancer. 2019. PMID: 31815181 Free PMC article.
Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor Mediated Activities in Breast Cancer Cells.
Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Min J, et al. Among authors: guillen vs. J Med Chem. 2017 Jul 27;60(14):6321-6336. doi: 10.1021/acs.jmedchem.7b00585. Epub 2017 Jul 14. J Med Chem. 2017. PMID: 28657320 Free PMC article.
Structurally Novel Antiestrogens Elicit Differential Responses from Constitutively Active Mutant Estrogen Receptors in Breast Cancer Cells and Tumors.
Zhao Y, Laws MJ, Guillen VS, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA, Katzenellenbogen BS. Zhao Y, et al. Among authors: guillen vs. Cancer Res. 2017 Oct 15;77(20):5602-5613. doi: 10.1158/0008-5472.CAN-17-1265. Epub 2017 Sep 13. Cancer Res. 2017. PMID: 28904064 Free PMC article.