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Role of CX3CR1 signaling in malignant transformation of gliomas.
Lee S, Latha K, Manyam G, Yang Y, Rao A, Rao G. Lee S, et al. Neuro Oncol. 2020 Oct 14;22(10):1463-1473. doi: 10.1093/neuonc/noaa075. Neuro Oncol. 2020. PMID: 32236410 Free PMC article.
A genetically engineered mouse model was leveraged to model endogenous intracranial gliomas with targeted expression of CX3C ligand 1 (CX3CL1) and CX3CR1, individually or in combination. RESULTS: LGG patients who were heterozygous (V/I; n = 43) or homozygous (I/I; …
A genetically engineered mouse model was leveraged to model endogenous intracranial gliomas with targeted expression of CX3C ligand 1 (CX3CL …