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Year Number of Results
1975 1
1977 1
1979 1
1981 1
1984 1
1987 1
1988 1
1991 3
1992 1
1993 2
1994 2
1995 4
1996 2
1997 2
1998 2
1999 1
2000 3
2001 3
2002 10
2003 5
2004 10
2005 7
2006 9
2007 15
2008 12
2009 17
2010 12
2011 26
2012 32
2013 29
2014 25
2015 30
2016 36
2017 33
2018 39
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2024 13

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512 results

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Page 1
Showing results for vitro h. Rodrigues
Search for Vítor H. Rodrigues instead (2 results)
Extracellular Vesicles Regulate Biofilm Formation and Yeast-to-Hypha Differentiation in Candida albicans.
Honorato L, de Araujo JFD, Ellis CC, Piffer AC, Pereira Y, Frases S, de Sousa Araújo GR, Pontes B, Mendes MT, Pereira MD, Guimarães AJ, da Silva NM, Vargas G, Joffe L, Del Poeta M, Nosanchuk JD, Zamith-Miranda D, Dos Reis FCG, de Oliveira HC, Rodrigues ML, de Toledo Martins S, Alves LR, Almeida IC, Nimrichter L. Honorato L, et al. mBio. 2022 Jun 28;13(3):e0030122. doi: 10.1128/mbio.00301-22. Epub 2022 Apr 14. mBio. 2022. PMID: 35420476 Free PMC article.
C. albicans EVs from distinct strains inhibited yeast-to-hyphae differentiation with morphological changes occurring in less than 4 h. EVs from S. cerevisiae and H. capsulatum modestly reduced morphogenesis, and the effect was evident after 24 h of incubation …
C. albicans EVs from distinct strains inhibited yeast-to-hyphae differentiation with morphological changes occurring in less than 4 h …
In vitro assessment of hepatotoxicity by metabolomics: a review.
Cuykx M, Rodrigues RM, Laukens K, Vanhaecke T, Covaci A. Cuykx M, et al. Arch Toxicol. 2018 Oct;92(10):3007-3029. doi: 10.1007/s00204-018-2286-9. Epub 2018 Aug 25. Arch Toxicol. 2018. PMID: 30155722 Review.
Omics technologies, and in particular metabolomics, have received an increasing attention during the assessment of hepatotoxicity in vitro. However, at present, a consensus on good metabolomics practices has yet to be reached. ...The most frequently reported metabolites th …
Omics technologies, and in particular metabolomics, have received an increasing attention during the assessment of hepatotoxicity in vitr …
Role of Cystathionine β-Synthase and 3-Mercaptopyruvate Sulfurtransferase in the Regulation of Proliferation, Migration, and Bioenergetics of Murine Breast Cancer Cells.
Santos SS, Rodrigues LOCP, Martins V, Petrosino M, Zuhra K, Ascenção K, Anand A, Abdel-Kader RM, Gad MZ, Bourquin C, Szabo C. Santos SS, et al. Antioxidants (Basel). 2023 Mar 5;12(3):647. doi: 10.3390/antiox12030647. Antioxidants (Basel). 2023. PMID: 36978895 Free PMC article.
The CBS/CSE inhibitor aminooxyacetic acid (AOAA) and the 3-MST inhibitor 2-[(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(naphthalen-1-yl)ethan-1-one (HMPSNE) were used to assess the role of endogenous H(2)S in the modulation of breast cancer cell proliferation, migration …
The CBS/CSE inhibitor aminooxyacetic acid (AOAA) and the 3-MST inhibitor 2-[(4-hydroxy-6-methylpyrimidin-2-yl)sulfanyl]-1-(naphthalen-1-yl)e …
A3907, a systemic ASBT inhibitor, improves cholestasis in mice by multiorgan activity and shows translational relevance to humans.
Caballero-Camino FJ, Rodrigues PM, Wångsell F, Agirre-Lizaso A, Olaizola P, Izquierdo-Sanchez L, Perugorria MJ, Bujanda L, Angelin B, Straniero S, Wallebäck A, Starke I, Gillberg PG, Strängberg E, Bonn B, Mattsson JP, Madsen MR, Hansen HH, Lindström E, Åkerblad P, Banales JM. Caballero-Camino FJ, et al. Hepatology. 2023 Sep 1;78(3):709-726. doi: 10.1097/HEP.0000000000000376. Epub 2023 Apr 1. Hepatology. 2023. PMID: 36999529 Free PMC article.
APPROACH AND RESULTS: A3907 was a potent and selective ASBT inhibitor in vitro. In rodents, orally administered A3907 distributed to the ASBT-expressing organs, that is, ileum, liver, and kidneys, and dose dependently increased fecal BA excretion. A3907 improved biochemica …
APPROACH AND RESULTS: A3907 was a potent and selective ASBT inhibitor in vitro. In rodents, orally administered A3907 distributed to …
In silico, in vitro, and in vivo investigation of antioxidant potential and toxicity of ethyl ferulate.
Bomfim de Sá C, Brito Lira A, Filho AAO, de Oliveira KM, Rolim da Paz A, Castro de Morais M, de Sousa DP, Tafaela Dias G, Rodrigues Melo C, Pessôa HLF, Maria Bezerra Luna Lima C, de Fátima Formiga Melo Diniz M. Bomfim de Sá C, et al. Drug Chem Toxicol. 2022 Jul;45(4):1769-1779. doi: 10.1080/01480545.2021.1878207. Epub 2021 Feb 25. Drug Chem Toxicol. 2022. PMID: 33632037 Review.
PhD student Andressa Brito Lira participated in the critical review of the text for important intellectual content and assisted in the in vitro antioxidant activity and cytotoxicity tests. Kardilandia Mendes de Oliveira participated in acute oral toxicity tests evaluating …
PhD student Andressa Brito Lira participated in the critical review of the text for important intellectual content and assisted in the in …
Somatic gene mutations expose cytoplasmic DNA to co-opt the cGAS/STING/NLRP3 axis in myelodysplastic syndromes.
McLemore AF, Hou HA, Meyer BS, Lam NB, Ward GA, Aldrich AL, Rodrigues MA, Vedder A, Zhang L, Padron E, Vincelette ND, Sallman DA, Abdel-Wahab O, List AF, McGraw KL. McLemore AF, et al. JCI Insight. 2022 Aug 8;7(15):e159430. doi: 10.1172/jci.insight.159430. JCI Insight. 2022. PMID: 35788117 Free PMC article.
Mechanistically, caspase-1 degraded the master erythroid transcription factor, GATA binding protein 1, provoking anemia and myeloid lineage bias that was reversed by cGAS inhibition in vitro and in Tet2-/- hematopoietic stem and progenitor cell-transplanted mice. ...
Mechanistically, caspase-1 degraded the master erythroid transcription factor, GATA binding protein 1, provoking anemia and myeloid lineage …
Activation of VIPR1 suppresses hepatocellular carcinoma progression by regulating arginine and pyrimidine metabolism.
Fu Y, Liu S, Rodrigues RM, Han Y, Guo C, Zhu Z, He Y, Mackowiak B, Feng D, Gao B, Zeng S, Shen H. Fu Y, et al. Int J Biol Sci. 2022 Jul 4;18(11):4341-4356. doi: 10.7150/ijbs.71134. eCollection 2022. Int J Biol Sci. 2022. PMID: 35864952 Free PMC article.
Approach and results: By analyzing clinical samples, we found the expression level of VIPR1 was downregulated in human HCC tissues, which was correlated with advanced clinical stages, tumor growth, recurrence, and poor outcomes of HCC clinically. In vitro and in vivo studi …
Approach and results: By analyzing clinical samples, we found the expression level of VIPR1 was downregulated in human HCC tissues, which wa …
Cynomolgus Monkey as an Emerging Animal Model to Study Drug Transporters: In Vitro, In Vivo, In Vitro-to-In Vivo Translation.
Shen H, Yang Z, Rodrigues AD. Shen H, et al. Drug Metab Dispos. 2022 Mar;50(3):299-319. doi: 10.1124/dmd.121.000695. Epub 2021 Dec 10. Drug Metab Dispos. 2022. PMID: 34893475 Review.
Burgeoning reports of data in the last few years necessitates a comprehensive review on the topic of drug transporters in cynomolgus monkeys that includes cell-based tools, sequence homology, tissue expression, in vitro studies, in vivo studies, and in vitro-to-in v …
Burgeoning reports of data in the last few years necessitates a comprehensive review on the topic of drug transporters in cynomolgus monkeys …
The mammalian peroxisomal membrane is permeable to both GSH and GSSG - Implications for intraperoxisomal redox homeostasis.
Ferreira MJ, Rodrigues TA, Pedrosa AG, Gales L, Salvador A, Francisco T, Azevedo JE. Ferreira MJ, et al. Redox Biol. 2023 Jul;63:102764. doi: 10.1016/j.redox.2023.102764. Epub 2023 May 25. Redox Biol. 2023. PMID: 37257275 Free PMC article.
Despite the large amounts of H(2)O(2) generated in mammalian peroxisomes, cysteine residues of intraperoxisomal proteins are maintained in a reduced state. ...or "is there a thiol-disulfide oxidoreductase in the organelle matrix?" still have no answer. We used a cell-free …
Despite the large amounts of H(2)O(2) generated in mammalian peroxisomes, cysteine residues of intraperoxisomal proteins are maintain …
Systematic Analysis of Monoterpenes: Advances and Challenges in the Treatment of Peptic Ulcer Diseases.
Périco LL, Emílio-Silva MT, Ohara R, Rodrigues VP, Bueno G, Barbosa-Filho JM, Rocha LRMD, Batista LM, Hiruma-Lima CA. Périco LL, et al. Biomolecules. 2020 Feb 10;10(2):265. doi: 10.3390/biom10020265. Biomolecules. 2020. PMID: 32050614 Free PMC article. Review.
However, this disease continues to be a challenge due to side-effects, incidence of relapse from use of various anti-ulcer medicines, and the rapid appearance of antimicrobial resistance with current H. pylori therapies. Consequently, there is the need to identify more eff …
However, this disease continues to be a challenge due to side-effects, incidence of relapse from use of various anti-ulcer medicines, and th …
512 results