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A Chemical Toolbox for Labeling and Degrading Engineered Cas Proteins.
Gama-Brambila RA, Chen J, Dabiri Y, Tascher G, Němec V, Münch C, Song G, Knapp S, Cheng X. Gama-Brambila RA, et al. Among authors: nemec v. JACS Au. 2021 May 12;1(6):777-785. doi: 10.1021/jacsau.1c00007. eCollection 2021 Jun 28. JACS Au. 2021. PMID: 34467332 Free PMC article.
Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
Němec V, Hylsová M, Maier L, Flegel J, Sievers S, Ziegler S, Schröder M, Berger BT, Chaikuad A, Valčíková B, Uldrijan S, Drápela S, Souček K, Waldmann H, Knapp S, Paruch K. Němec V, et al. Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1062-1066. doi: 10.1002/anie.201810312. Epub 2018 Dec 20. Angew Chem Int Ed Engl. 2019. PMID: 30569600
Site-specific analysis of protein hydration based on unnatural amino acid fluorescence.
Amaro M, Brezovský J, Kováčová S, Sýkora J, Bednář D, Němec V, Lišková V, Kurumbang NP, Beerens K, Chaloupková R, Paruch K, Hof M, Damborský J. Amaro M, et al. Among authors: nemec v. J Am Chem Soc. 2015 Apr 22;137(15):4988-92. doi: 10.1021/jacs.5b01681. Epub 2015 Apr 9. J Am Chem Soc. 2015. PMID: 25815779