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Page 1
Hereditary diffuse gastric cancer: updated clinical practice guidelines.
Lancet Oncol. 2020 Aug;21(8):e386-e397. doi: 10.1016/S1470-2045(20)30219-9.
Lancet Oncol. 2020.
PMID: 32758476
Free PMC article.
Review.
E-Cadherin-Deficient Epithelial Cells Are Sensitive to HDAC Inhibitors.
Decourtye-Espiard L, Bougen-Zhukov N, Godwin T, Brew T, Schulpen E, Black MA, Guilford P.
Decourtye-Espiard L, et al. Among authors: brew t.
Cancers (Basel). 2021 Dec 30;14(1):175. doi: 10.3390/cancers14010175.
Cancers (Basel). 2021.
PMID: 35008338
Free PMC article.
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Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing.
Dixon K, Brew T, Farnell D, Godwin TD, Cheung S, Chow C, Ta M, Ho G, Bui M, Douglas JM, Campbell KR, El-Naggar A, Kaurah P, Kalloger SE, Lim HJ, Schaeffer DF, Cochrane D, Guilford P, Huntsman DG.
Dixon K, et al. Among authors: brew t.
J Pathol. 2021 Jul;254(3):254-264. doi: 10.1002/path.5675. Epub 2021 May 12.
J Pathol. 2021.
PMID: 33797756
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Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient Cells.
Bougen-Zhukov N, Nouri Y, Godwin T, Taylor M, Hakkaart C, Single A, Brew T, Permina E, Chen A, Black MA, Guilford P.
Bougen-Zhukov N, et al. Among authors: brew t.
Cancers (Basel). 2019 Sep 13;11(9):1359. doi: 10.3390/cancers11091359.
Cancers (Basel). 2019.
PMID: 31540244
Free PMC article.
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Loss of E-Cadherin Leads to Druggable Vulnerabilities in Sphingolipid Metabolism and Vesicle Trafficking.
Brew T, Bougen-Zhukov N, Mitchell W, Decourtye L, Schulpen E, Nouri Y, Godwin T, Guilford P.
Brew T, et al.
Cancers (Basel). 2021 Dec 26;14(1):102. doi: 10.3390/cancers14010102.
Cancers (Basel). 2021.
PMID: 35008266
Free PMC article.
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E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function.
Godwin TD, Kelly ST, Brew TP, Bougen-Zhukov NM, Single AB, Chen A, Stylianou CE, Harris LD, Currie SK, Telford BJ, Beetham HG, Evans GB, Black MA, Guilford PJ.
Godwin TD, et al. Among authors: brew tp.
Gastric Cancer. 2019 Mar;22(2):273-286. doi: 10.1007/s10120-018-0859-1. Epub 2018 Jul 31.
Gastric Cancer. 2019.
PMID: 30066183
Free PMC article.
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Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells.
Telford BJ, Chen A, Beetham H, Frick J, Brew TP, Gould CM, Single A, Godwin T, Simpson KJ, Guilford P.
Telford BJ, et al. Among authors: brew tp.
Mol Cancer Ther. 2015 May;14(5):1213-23. doi: 10.1158/1535-7163.MCT-14-1092. Epub 2015 Mar 16.
Mol Cancer Ther. 2015.
PMID: 25777964
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