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The Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimers Disease.
Grimm MO, Mett J, Hartmann T. Grimm MO, et al. Int J Mol Sci. 2016 Oct 26;17(11):1785. doi: 10.3390/ijms17111785. Int J Mol Sci. 2016. PMID: 27792188 Free PMC article. Review.
Several vitamins have been reported to be reduced in the plasma/serum of AD-affected individuals indicating they have an impact on AD pathogenesis. In this review we focus on vitamin E and the other lipophilic vitamins A, D, and K, and summarize the current knowledge about …
Several vitamins have been reported to be reduced in the plasma/serum of AD-affected individuals indicating they have an impact on AD pathog …
Role of amyloid precursor protein, amyloid-beta and gamma-secretase in cholesterol maintenance.
Hartmann T. Hartmann T. Neurodegener Dis. 2006;3(4-5):305-11. doi: 10.1159/000095271. Neurodegener Dis. 2006. PMID: 17047372 Review.
An understanding of the physiological function of amyloid precursor protein processing and Abeta function is critical for the development of future therapeutic approaches, e.g. statin treatment....
An understanding of the physiological function of amyloid precursor protein processing and Abeta function is critical for the development of …
Tocotrienol Affects Oxidative Stress, Cholesterol Homeostasis and the Amyloidogenic Pathway in Neuroblastoma Cells: Consequences for Alzheimer's Disease.
Grimm MO, Regner L, Mett J, Stahlmann CP, Schorr P, Nelke C, Streidenberger O, Stoetzel H, Winkler J, Zaidan SR, Thiel A, Endres K, Grimm HS, Volmer DA, Hartmann T. Grimm MO, et al. Int J Mol Sci. 2016 Oct 29;17(11):1809. doi: 10.3390/ijms17111809. Int J Mol Sci. 2016. PMID: 27801864 Free PMC article.
One of the characteristics of Alzheimers disease (AD) is an increased amyloid load and an enhanced level of reactive oxidative species (ROS). Vitamin E has known beneficial neuroprotective effects, and previously, some studies suggested that vitamin E is associated …
One of the characteristics of Alzheimers disease (AD) is an increased amyloid load and an enhanced level of reactive oxidative species (ROS) …
Non-structural carbohydrates in woody plants compared among laboratories.
Quentin AG, Pinkard EA, Ryan MG, Tissue DT, Baggett LS, Adams HD, Maillard P, Marchand J, Landhäusser SM, Lacointe A, Gibon Y, Anderegg WR, Asao S, Atkin OK, Bonhomme M, Claye C, Chow PS, Clément-Vidal A, Davies NW, Dickman LT, Dumbur R, Ellsworth DS, Falk K, Galiano L, Grünzweig JM, Hartmann H, Hoch G, Hood S, Jones JE, Koike T, Kuhlmann I, Lloret F, Maestro M, Mansfield SD, Martínez-Vilalta J, Maucourt M, McDowell NG, Moing A, Muller B, Nebauer SG, Niinemets Ü, Palacio S, Piper F, Raveh E, Richter A, Rolland G, Rosas T, Saint Joanis B, Sala A, Smith RA, Sterck F, Stinziano JR, Tobias M, Unda F, Watanabe M, Way DA, Weerasinghe LK, Wild B, Wiley E, Woodruff DR. Quentin AG, et al. Tree Physiol. 2015 Nov;35(11):1146-65. doi: 10.1093/treephys/tpv073. Epub 2015 Sep 29. Tree Physiol. 2015. PMID: 26423132
Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
Herold T, Schneider S, Metzeler KH, Neumann M, Hartmann L, Roberts KG, Konstandin NP, Greif PA, Bräundl K, Ksienzyk B, Huk N, Schneider I, Zellmeier E, Jurinovic V, Mansmann U, Hiddemann W, Mullighan CG, Bohlander SK, Spiekermann K, Hoelzer D, Brüggemann M, Baldus CD, Dreyling M, Gökbuget N. Herold T, et al. Haematologica. 2017 Jan;102(1):130-138. doi: 10.3324/haematol.2015.136366. Epub 2016 Aug 25. Haematologica. 2017. PMID: 27561722 Free PMC article.
The complete remission rate was 100% among both Ph-like ALL patients (n=19) and the "remaining BCP-ALL" cases (n=40), i.e. patients negative for BCR-ABL1 and KMT2A-rearrangements and the Ph-like subtype. ...
The complete remission rate was 100% among both Ph-like ALL patients (n=19) and the "remaining BCP-ALL" cases (n=40), i.e. patients n …