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The Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels.
Barrett CF, Tsien RW. Barrett CF, et al. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2157-62. doi: 10.1073/pnas.0710501105. Epub 2008 Feb 4. Proc Natl Acad Sci U S A. 2008. PMID: 18250309 Free PMC article.
Inactivation of Ca2+ channel activity is perturbed in a rare yet devastating disorder known as Timothy syndrome (TS), whose features include autism or autism spectrum disorder along with severe cardiac arrhythmia and developmental abnormalities. ...
Inactivation of Ca2+ channel activity is perturbed in a rare yet devastating disorder known as Timothy syndrome (TS), whose features …
Elevated serum gastrin is associated with a history of advanced neoplasia in Barrett's esophagus.
Wang JS, Varro A, Lightdale CJ, Lertkowit N, Slack KN, Fingerhood ML, Tsai WY, Wang TC, Abrams JA. Wang JS, et al. Am J Gastroenterol. 2010 May;105(5):1039-45. doi: 10.1038/ajg.2009.629. Epub 2009 Nov 10. Am J Gastroenterol. 2010. PMID: 19904251 Free PMC article.
OBJECTIVES: Proton pump inhibitors (PPIs) are frequently prescribed to patients with Barrett's esophagus (BE), but in a subset, they can induce significant hypergastrinemia. ...
OBJECTIVES: Proton pump inhibitors (PPIs) are frequently prescribed to patients with Barrett's esophagus (BE), but in a subset, they …