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Bimatoprost/timolol fixed combination: a 3-month double-masked, randomized parallel comparison to its individual components in patients with glaucoma or ocular hypertension.
Brandt JD, Cantor LB, Katz LJ, Batoosingh AL, Chou C, Bossowska I; Ganfort Investigators Group II. Brandt JD, et al. J Glaucoma. 2008 Apr-May;17(3):211-6. doi: 10.1097/IJG.0b013e3181507313. J Glaucoma. 2008. PMID: 18414107 Clinical Trial.
BIM and FC vs. TIM). The proportion of patients achieving an IOP of less than 18 mm Hg at all time points was 39.2% (209/533), 28.7% (76/265), and 12.2% (32/263) for the FC, BIM, and TIM groups, respectively (P=0.003 for FC vs. ...BIM) and TIM (6.8%, 18/263; …
BIM and FC vs. TIM). The proportion of patients achieving an IOP of less than 18 mm Hg at all time points was 39.2% (209/533), 28.7% …
Intratumoral regulatory T cells upregulate immunosuppressive molecules in head and neck cancer patients.
Jie HB, Gildener-Leapman N, Li J, Srivastava RM, Gibson SP, Whiteside TL, Ferris RL. Jie HB, et al. Br J Cancer. 2013 Nov 12;109(10):2629-35. doi: 10.1038/bjc.2013.645. Epub 2013 Oct 29. Br J Cancer. 2013. PMID: 24169351 Free PMC article.
RESULTS: The frequency of immune-checkpoint receptor-positive cells was higher on intratumoral FOXP3(+)CD25(hi) Treg compared with circulating Treg (CTLA-4, P=0.002; TIM-3, P=0.002 and PD-1, P=0.002). Immunosuppressive effector molecules, LAP and ectonucleotidase CD39 were …
RESULTS: The frequency of immune-checkpoint receptor-positive cells was higher on intratumoral FOXP3(+)CD25(hi) Treg compared with circulati …