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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
2009 5
2010 4
2011 4
2012 2
2013 2
2014 2
2015 3
2016 2
2017 2
2019 2
2020 1
2021 1
2022 2
2024 0

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29 results

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Page 1
Modulating mitofusins to control mitochondrial function and signaling.
Zacharioudakis E, Agianian B, Kumar Mv V, Biris N, Garner TP, Rabinovich-Nikitin I, Ouchida AT, Margulets V, Nordstrøm LU, Riley JS, Dolgalev I, Chen Y, Wittig AJH, Pekson R, Mathew C, Wei P, Tsirigos A, Tait SWG, Kirshenbaum LA, Kitsis RN, Gavathiotis E. Zacharioudakis E, et al. Among authors: garner tp. Nat Commun. 2022 Jul 7;13(1):3775. doi: 10.1038/s41467-022-31324-1. Nat Commun. 2022. PMID: 35798717 Free PMC article.
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.
Gomez-Sintes R, Xin Q, Jimenez-Loygorri JI, McCabe M, Diaz A, Garner TP, Cotto-Rios XM, Wu Y, Dong S, Reynolds CA, Patel B, de la Villa P, Macian F, Boya P, Gavathiotis E, Cuervo AM. Gomez-Sintes R, et al. Among authors: garner tp. Nat Commun. 2022 Jul 21;13(1):4220. doi: 10.1038/s41467-022-31869-1. Nat Commun. 2022. PMID: 35864098 Free PMC article.
Progress in targeting the BCL-2 family of proteins.
Garner TP, Lopez A, Reyna DE, Spitz AZ, Gavathiotis E. Garner TP, et al. Curr Opin Chem Biol. 2017 Aug;39:133-142. doi: 10.1016/j.cbpa.2017.06.014. Epub 2017 Aug 17. Curr Opin Chem Biol. 2017. PMID: 28735187 Free PMC article. Review.
Small-molecule allosteric inhibitors of BAX.
Garner TP, Amgalan D, Reyna DE, Li S, Kitsis RN, Gavathiotis E. Garner TP, et al. Nat Chem Biol. 2019 Apr;15(4):322-330. doi: 10.1038/s41589-018-0223-0. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718816 Free PMC article.
Eltrombopag directly inhibits BAX and prevents cell death.
Spitz AZ, Zacharioudakis E, Reyna DE, Garner TP, Gavathiotis E. Spitz AZ, et al. Among authors: garner tp. Nat Commun. 2021 Feb 18;12(1):1134. doi: 10.1038/s41467-021-21224-1. Nat Commun. 2021. PMID: 33602934 Free PMC article.
A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy.
Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari SR, Mitchell K, Lopez A, Margulets V, Scarlata M, Santulli G, Asnani A, Peterson RT, Hazan RB, Condeelis JS, Oktay MH, Steidl U, Kirshenbaum LA, Gavathiotis E, Kitsis RN. Amgalan D, et al. Among authors: garner tp. Nat Cancer. 2020 Mar;1(3):315-328. doi: 10.1038/s43018-020-0039-1. Epub 2020 Mar 2. Nat Cancer. 2020. PMID: 32776015 Free PMC article.
Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism.
Barclay LA, Wales TE, Garner TP, Wachter F, Lee S, Guerra RM, Stewart ML, Braun CR, Bird GH, Gavathiotis E, Engen JR, Walensky LD. Barclay LA, et al. Among authors: garner tp. Mol Cell. 2015 Mar 5;57(5):873-886. doi: 10.1016/j.molcel.2015.01.014. Epub 2015 Feb 12. Mol Cell. 2015. PMID: 25684204 Free PMC article.
An Autoinhibited Dimeric Form of BAX Regulates the BAX Activation Pathway.
Garner TP, Reyna DE, Priyadarshi A, Chen HC, Li S, Wu Y, Ganesan YT, Malashkevich VN, Cheng EH, Gavathiotis E. Garner TP, et al. Mol Cell. 2016 Aug 4;63(3):485-97. doi: 10.1016/j.molcel.2016.06.010. Epub 2016 Jul 14. Mol Cell. 2016. PMID: 27425408 Free PMC article.
29 results